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Usage

Uses

Used in Pharmaceutical Development:
2-(piperidin-1-yl)anthracene-9,10-dione is used as a potential candidate for pharmaceutical development due to its enhanced pharmacological properties resulting from the incorporation of the piperidine ring. This modification can improve the solubility, potency, and selectivity of the compound, making it a promising agent for the treatment of various diseases.
Used in Anticancer Applications:
As a derivative of anthracenediones, 2-(piperidin-1-yl)anthracene-9,10-dione is used as an anticancer agent. Its potential therapeutic applications in the treatment of various cancers can be attributed to the known anticancer activity of anthracenediones and the additional benefits provided by the piperidine ring.
Used in Drug Delivery Systems:
Further research and development of 2-(piperidin-1-yl)anthracene-9,10-dione could lead to the discovery of novel pharmaceutical agents with improved efficacy and reduced side effects. The development of drug delivery systems, such as organic and metallic nanoparticles, can enhance the delivery, bioavailability, and therapeutic outcomes of 2-(piperidin-1-yl)anthracene-9,10-dione, making it a valuable asset in the field of medicine.

Upstream product

• 110-86-1 pyridine 
• 84-65-1 9,10-phenanthrenequinone 
• 110-89-4 piperidine 
• 131-09-9 2-chloroanthracene-9,10-dione 

Relevant academic research and scientific papers

Amide Ion Formation and N-Alkylation of Aminoanthraquinones in the presence of Potassium Hydroxide in Dimethyl Sulfoxide

Amide ions were formed by the deprotonation of the amino group of amino group of amino- and (monoalkylamino)anthroquinones in the presence of powdered potassium hydroxide in dimethyl sulfoxide (DMSO).Under a nitrogen atmosphere these amide ions changed to their radical anions.The amide ions of 1-aminoanthroquinones reacted with excess alkyl halides to yield 1-alkylaminoanthraquinones, while the N-alkylation of 2-aminoanthraquinones afforded 2-alkylaminoanthraquinones in good yields. 2-Aminobenzophenone underwent mono-N-alkylation, while 4-aminoazobenzene and p-nitroaniline underwent di-N-alkylation.It was also found that carbanion of DMSO easily attacked the carbonyl group of the (dialkylamino)anthraquinones.

PHOTOCHEMICAL REACTION OF 9,10-ANTHRAQUINONE AND ITS DERIVATIVES WITH PYRIDINE

The previously unknown photochemical reaction of 9,10-anthraquinone with pyridine in an atmosphere of argon takes place with formation of 2-(1,2-dihydropyridino)- or 2-(1,4-dihydropyridino)-9,10-anthraquinone, which is converted by the action of alkali into 2-aminoanthraquinone.In the presence of atmospheric oxygen the reaction product after treatment whith alkali is 1-aminoanthraquinone in addition to 2-aminoanthraquinone.The 1- and 2-methoxyanthraquinones and chloroanthraquinones react with pyridine in the light and form, after treatment with alkali, substituted aminoanthraquinones.