6345-88-6

Usage

Uses

Used in Pharmaceutical Research:
2-(2-hydroxyethyl)-1H-benzo[f]isoindole-1,3(2H)-dione is used as a research compound for investigating its potential therapeutic effects on various mental health conditions. It is particularly focused on its role as a selective serotonin receptor agonist, which may help in understanding and treating depression, anxiety, and sleep disorders.
Used in Neuroscience:
2-(2-hydroxyethyl)-1H-benzo[f]isoindole-1,3(2H)-dione is used as a research tool in neuroscience to explore its potential role in regulating mood, appetite, and circadian rhythms. 2-(2-hydroxyethyl)-1H-benzo[f]isoindole-1,3(2H)-dione may provide insights into the underlying mechanisms of these physiological processes and contribute to the development of new therapeutic strategies for related disorders.
Used in Drug Development:
2-(2-hydroxyethyl)-1H-benzo[f]isoindole-1,3(2H)-dione is used as a lead compound in the development of new drugs targeting serotonin receptors. Its potential therapeutic applications in treating mental health conditions, such as depression and anxiety, make it a valuable candidate for further research and development in the pharmaceutical industry.

Upstream product

• 716-39-2 2,3-Naphthalenedicarboxylic anhydride 
• 141-43-5 ethanolamine 
• 2169-87-1 naphthalene-2,3-dicarboxylic acid 

Downstream Products

• 77766-23-5 2-tosyloxyethyl-naphthalene-2,3-dicarboxylic imide 

Relevant academic research and scientific papers

Versatile Room-Temperature-Phosphorescent Materials Prepared from N-Substituted Naphthalimides: Emission Enhancement and Chemical Conjugation

Purely organic materials with room-temperature phosphorescence (RTP) are currently under intense investigation because of their potential applications in sensing, imaging, and displaying. Inspired by certain organometallic systems, where ligand-localized

AMINOPHTHALAZINONE DERIVATIVES, VI; SYNTHESIS OF 4-(HYDROXYALKYLAMINO)-BENZO-1(2H)-PHTHALAZINONES

The methods developed from procedures published earlier make possible the synthesis of various 4-(alkylamino-benzo-1(2H)-phthalazinones.Method A (1-->6, 7) is suitable for the incorporation of 1,2- or 1,3-aminoalcohols.When starting from N-β-tosyloxyalkylnaphthalene-2,3-dicarboxylic imides (2; M: -) and 3-bromo-propylimides (3b), parent compounds 6 and the compounds containing methyl, 2-hydroxyethyl and 2-diethylaminoethyl substituents at the N(2) position (7) are formed in excellent and medium yield, respectively.A greater variety of derivatives can be synthesized by Method B, since coupling of 4-chlorobenzo-1(2H)-phthalazinone (9) with aminoalcohols (9-->6a, 6f, 11, 12) is independent of the relative distance between the amino and hydroxy terminals, and the N-substitution (9-->13, 14) of hydroxy-free primary and secondary amines can also be achieved in ethylene glycol solutions.