634589-05-2Relevant academic research and scientific papers
Regio- and diastereoselective tandem addition-carbocyclization promoted by sulfanyl radicals on chiral perhydro-1,3-benzoxazines
Pedrosa, Rafael,Andres, Celia,Duque-Soladana, Juan P.,Maestro, Alicia,Nieto, Javier
, p. 2985 - 2990 (2007/10/03)
Radical addition-carbocyclization of 2-allyl-3-acyloyl-substituted perhydro-1,3-benzoxazines readily provides 3,4-disubstituted pyrrolidinone derivatives with total regioselectivity and good diastereoselectivity. The key step of the reaction is a tandem addition-5-exo-cyclization promoted by a sulfanyl radical.
