634603-67-1

Upstream product

• 508191-77-3 3-phenylsydnone 
• 188707-58-6 4-iodo-3-(2-iodophenyl)sydnone 

Downstream Products

• 634603-66-0 3-(2-(trimethylsilylethynyl)phenyl)sydnone 
• 634603-65-9 3-(2-ethynylphenyl)sydnone 
• 852336-08-4 3-(2-(4-bromophenylethynyl)phenyl)sydnone 
• 848085-15-4 3-(2-(4-(ethynyl)phenylethynyl)phenyl)sydnone 
• 852336-09-5 3-(2-(4-(trimethylsilylethynyl)phenylethynyl)phenyl)sydnone 
• 188707-58-6 4-iodo-3-(2-iodophenyl)sydnone 

Relevant academic research and scientific papers

The sydnone ring as an ortho-director of lithiation. 2. Dilithiation of 3-phenylsydnone and regiospecific @?o-aryl acylation using N-methoxy-N-methylamides

Readily available 3-phenylsydnone (1) reacts with n-butyllithium/TMEDA to form the dilithio species 2 which can be regiospecifically acylated at the ortho-aryl position using N-methoxy-N-methylamides (Weinreb's amides).

Routes to sydnone-containing oligomeric areneynes

Iterative Sonogashira-coupling routes have been used to prepare sydnone-containing areneynes 1-3 (and related compounds) from ?-iodophenylsydnone (4). The best results were obtained by using two- and three-reaction-in-one-pot protocols.