63472-02-6

Basic information

• Product Name: 2,2'-<4-Bisphenylylmethylen>bis(1,3-indandion)
• CAS NO: 63472-02-6
• Molecular Weight: 456.497
• Mol File: 63472-02-6.mol

Chemical Properties

• CAS DataBase Reference: 2,2'-<4-Bisphenylylmethylen>bis(1,3-indandion)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-<4-Bisphenylylmethylen>bis(1,3-indandion)(63472-02-6)
• EPA Substance Registry System: 2,2'-<4-Bisphenylylmethylen>bis(1,3-indandion)(63472-02-6)

Safety Data

• Hazardous Substances Data: 63472-02-6(Hazardous Substances Data)

Upstream product

• 606-23-5 1H-indene-1,3(2H)-dione 
• 3218-36-8 4-Phenylbenzaldehyde 

Relevant articles and documents

Fenbufen, a new anti inflammatory analgesic: synthesis and structure activity relationships of analogs

100 analogs of fenbufen were prepared and tested using the carrageenan, polyarthritis, and UV erythema anti inflammatory tests and the 2 phenyl 1,4 benzoquinone writhing and inflamed paw pressure analgesic tests. Only 3 retained the same full spectrum of activity as fenbufen: dl 4 (4 biphenylyl) 4 hydroxybutyric acid, dl 4 (4 biphenylyl) 1,4 butanediol, and 4 biphenylacetic acid. Fenbufen had the same spectrum of activity as aspirin, phenylbutazone, and indomethacin in the 5 tests. In addition, dose response derived potencies show fenbufen more potent than aspirin and at least as potent as phenylbutazone in all 5 tests. Two related compounds were generally similar.