63473-97-2Relevant academic research and scientific papers
Microwave-assisted ring opening of epoxides: A general route to the synthesis of 1-aminopropan-2-ols with anti malaria parasite activities
Robin, Aélig,Brown, Fraser,Bahamontes-Rosa, Noemí,Wu, Binghua,Beitz, Eric,Kun, Jürgen F. J.,Flitsch, Sabine L.
, p. 4243 - 4249 (2008/02/12)
A series of 1-aminopropan-2-ols were synthesized and evaluated against two strains of malaria, Plasmodium falciparum FCR3 (chloroquine-resistant) and 3D7 (chloroquine-sensitive). Microwave-assisted ring opening of epoxides (aryl and alkyl glycidyl ethers,
Regioselective ring opening of epoxides by nucleophiles mediated by lithium bistrifluoromethanesulfonimide
Cossy, Janine,Bellosta, Véronique,Hamoir, Claire,Desmurs, Jean-Roger
, p. 7083 - 7086 (2007/10/03)
In the presence of LiNTf2, epoxides undergo ring opening with high regioselectivity and in good yield when they are treated with nucleophiles such as amines, hydrazines and thiophenol.
Nucleophilic Addition to Cyclic 1,2-Sulfites
Carlsen, Per H.,Aase, Kristin J.
, p. 617 - 619 (2007/10/02)
Addition of heteroatom nucleophiles has been shown to attack at either the C5- or the S-atom sites in 4-(benzyloxymethyl)-1,3-dioxa-2-thiolane 2-oxide.No C4-reactivity was observed.The regioselectivity depended on the type of nucleophile.
