63474-91-9

Upstream product

• 64-17-5 ethanol 
• 52-67-5 3,3-dimethyl-D-cysteine 

Downstream Products

• 81057-39-8 (2R,4S)-2-(2-Hydroxy-5-nitro-phenyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid ethyl ester 
• 81057-37-6 (2S,4S)-2-(2-Hydroxy-5-nitro-phenyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid ethyl ester 
• 81057-43-4 (2R,4S)-3-(2-Chloro-acetyl)-2-(2-hydroxy-5-nitro-phenyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid ethyl ester 
• 81057-41-2 (2S,4S)-3-(2-Chloro-acetyl)-2-(2-hydroxy-5-nitro-phenyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid ethyl ester 
• 81057-38-7 (2R,4S)-2-(5-Chloro-2-hydroxy-phenyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid ethyl ester 
• 81066-52-6 (2S,4S)-2-(5-Chloro-2-hydroxy-phenyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid ethyl ester 
• 81057-42-3 (2R,4S)-3-(2-Chloro-acetyl)-2-(5-chloro-2-hydroxy-phenyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid ethyl ester 
• 81057-40-1 (2S,4S)-3-(2-Chloro-acetyl)-2-(5-chloro-2-hydroxy-phenyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Sulfur-containing β-amino alcohols as catalysts in enantioselective synthesis

Oxazaborolidine catalysts generated in situ from cyclic or acyclic sulfur containing (R)-cysteine, (S)-penicillamine and (S)-methionine derivates and BH3 have been applied successfully to the enantiocontrolled, catalytic reduction of aromatic ketones. The corresponding sec alcohols could be obtained in excellent enantiomeric excess, up to 100% ee. Using these chiral auxiliaries in the enantioselective addition of diethylzinc to aldehydes afforded optically active sec alcohols in enantiomeric excess up to 93% ee.