63488-07-3Relevant academic research and scientific papers
Enantioselective synthesis of spirocyclic cyclopentenes: Asymmetric [3+2] annulation of 2-arylideneindane-1,3-diones with MBH carbonates derivatives catalyzed by multifunctional thiourea-phosphines
Hu, Fangle,Wei, Yin,Shi, Min
, p. 7911 - 7919 (2012)
The [3+2] annulation reactions of 2-arylideneindane-1,3-diones with Morita-Baylis-Hillman (MBH) carbonates proceeded smoothly in the presence of multifunctional thiourea-phosphines to produce the corresponding quaternary carbon centered spirocyclic cyclop
Highly diastereoselective spiro-cyclopropanation of 2-arylidene-1,3-indanediones and dimethylsulfonium ylides
Huang, Jie,Lee, Kevin,Ma, Ping,Sun, Shaofa,Wang, Gangqiang,Wang, Jian,Wu, Yang,Xing, Yalan
supporting information, p. 18776 - 18780 (2021/10/26)
A highly diastereoselective spiro-cyclopropanation reaction of 2-arylidene-1,3-indanediones and dimethylsulfonium ylides has been developedviabase-induced annulation. This efficient and simple protocol features simple operations, mild conditions and excellent functional group compatibility. A variety of structurally interesting spiro-cyclopropanes were prepared in excellent yields and diastereomeric ratios (up to 97% yield and 20?:?1 dr). Also, ring expansion of the cyclopropanation product to quickly deliver a complex indeno[1,2-c]pyridazine structure showcased an interesting application of this method.
