634893-97-3

Upstream product

• 120-74-1 (1S,2S,4S)-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid 

Downstream Products

• 634893-98-4 di-tert-butyl (8S)-8β-(benzyloxycarbonylmethylcarbamoyl)-4-oxa-(1α,2β,3α,5α,6β,7α)-tetracyclo[5.2.1.0^2,6.0^3,5]decane-3,5-dicarboxylate 
• 634893-99-5 di-tert-butyl (4S,11S)-4β-(benzyloxycarbonylmethylcarbamoyl)-11β-(1-methoxycarbonylethylcarbamoyl)-16-oxa-(1α,2β,3α,6α,7β,8α,9β,10α,13α,14β)-hexacyclo[6.6.1.1^4,6.1^10,13.0^2,7.0^9,14]heptadeca-1,8-dicarboxylate 

Relevant academic research and scientific papers

Strategies and methods for the attachment of amino acids and peptides to chiral [n]polynorbornane templates.

A versatile synthesis of amino acid and peptide functionalised [n]polynorbornane scaffolds is described. The frameworks are constructed using the stereoselective and regioselective cycloaddition of suitably functionalised chiral cyclobutene epoxides with similar norbornenes. The strategies employed allow a range of topologies to be accessed and a number of regioselectively addressable linkage points to be accommodated.