63495-40-9Relevant academic research and scientific papers
Catalytic removal of N-allyloxycarbonyl groups using the [CpRu(IV)(π-C3H5)(2-quinolinecarboxylato)]PF 6 complex. A new efficient deprotecting method in peptide synthesis
Tanaka, Shinji,Saburi, Hajime,Murase, Takanori,Yoshimura, Masahiro,Kitamura, Masato
, p. 4682 - 4684 (2006)
A variety of amines including even sterically less demanding and highly nucleophilic secondary amines have been efficiently deprotected without decarboxylative N-allylation from the corresponding N-allyloxycarbonyl (N-AOC) compounds by using a catalytic amount of [CpRu-(IV)(π-C3H 5)(2-quinolinecarboxylato)]PF6 in the presence of 1 molar amount of trifluoromethanesulfonic acid, the general utility of which has been demonstrated by the efficient synthesis of a collagen protein unit tripeptide, Pro-Pro-Gly.
