63502-76-1 Usage
General Description
1-Cyclohexyl-5-fluoro-2,4(1H,3H)-pyrimidinedione is a chemical compound with the molecular formula C11H12FN3O2. It is a pyrimidine derivative with a cyclohexyl group attached to the 1-position and a fluorine atom attached to the 5-position. 2,4(1H,3H)-Pyrimidinedione, 1-cyclohexyl-5-fluoro- is a hybrid of a pyrimidine and cyclohexane, making it useful in pharmaceutical research and drug development. It is known to have potential biological activities, especially in the field of anticancer drugs, due to its ability to target specific proteins in cancer cells. Additionally, it has shown potential as an anti-inflammatory and analgesic agent, making it an important compound in the study of various diseases and disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 63502-76-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,5,0 and 2 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 63502-76:
(7*6)+(6*3)+(5*5)+(4*0)+(3*2)+(2*7)+(1*6)=111
111 % 10 = 1
So 63502-76-1 is a valid CAS Registry Number.
63502-76-1Relevant articles and documents
Glorination of Pyrimidines. Part 2. Mechanistic Aspects of the Reaction of Acetyl Hypofluorite with Uracil and Cytosine Derivatives
Visser, W. M. Gerard,Herder, E. Renella,Kanter, Frans J. J. de,Herscheid D. M. Jacobus
, p. 1203 - 1208 (2007/10/02)
The reaction of acetyl hypofluorite (AcOF) with uracil, cytosine, and some N-1-substituted derivatives dissolved in either acetic acid or water has been investigated.Analysis by radio-h.p.l.c., using (18)f as a tracer, and by (1)H n.m.r. revealed that a substituent at N-1 of uracil has a remarkable effect on the stability of the intermediate 6-acetoxy-5-fluoro-5,6-dihydrouracils.In addition, it was found that these cytosine adducts rapidly deaminate in water yielding their corresponding uracil analogues.
