63503-32-2

Basic information

• Product Name: Phenyl-acetic acid (1R,7aR)-7-hydroxymethyl-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl ester
• CAS NO: 63503-32-2
• Molecular Weight: 273.332
• Mol File: 63503-32-2.mol

Chemical Properties

• CAS DataBase Reference: Phenyl-acetic acid (1R,7aR)-7-hydroxymethyl-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phenyl-acetic acid (1R,7aR)-7-hydroxymethyl-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl ester(63503-32-2)
• EPA Substance Registry System: Phenyl-acetic acid (1R,7aR)-7-hydroxymethyl-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl ester(63503-32-2)

Safety Data

• Hazardous Substances Data: 63503-32-2(Hazardous Substances Data)

Upstream product

• 103-82-2 phenylacetic acid 
• 480-85-3 retronecine 

Relevant articles and documents

Synthesis of pyrrolizidine alkaloids indicine, intermedine, lycopsamine, and analogues and their N-oxides. Potential antitumor agents

(-)- and (+)-trachelanthic and (-)- and (+)-viridifloric acids were synthesized and their isopropylidene derivatives were regiospecifically coupled, at C-9, with (-)-retronecine (2) obtained by hydrolysis of monocrotaline (1), isolated from Crotalaria spectabilis. Hydrolysis, followed by oxidation, led to the N-oxides of indicine (7), intermedine (13), lycopsamine (15), and the new nonnatural product 16, respectively. Each of these analogues was screened in the P388 lymphocytic leukemia system at the same time as indicine N-oxide, and the results were compared. Other related analogues were prepared and similarly screened and the results compared with those from indicine N-oxide.