63512-54-9

Basic information

• Product Name: 1-Amino-2-naphthalenethiol
• Synonyms: 1-Amino-2-naphthalenethiol
• CAS NO: 63512-54-9
• Molecular Formula: C₁₀H₉NS
• Molecular Weight: 175.25
• Mol File: 63512-54-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 346.8°C at 760 mmHg
• Flash Point: 163.5°C
• Appearance: /
• Density: 1.265g/cm³
• Vapor Pressure: 5.63E-05mmHg at 25°C
• Refractive Index: 1.751
• CAS DataBase Reference: 1-Amino-2-naphthalenethiol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Amino-2-naphthalenethiol(63512-54-9)
• EPA Substance Registry System: 1-Amino-2-naphthalenethiol(63512-54-9)

Safety Data

• Hazardous Substances Data: 63512-54-9(Hazardous Substances Data)

Usage

Physical state

Yellowish solid

Uses

Building block in the synthesis of dyes and other organic compounds

Odor

Strong

Applications

Production of antifungal agents, corrosion inhibitors, metal complexes, coordination compounds, biochemical research reagent, and chemiluminescent reactions component

Bonding

Forms strong covalent bonds with metals

Safety precautions

Potential to cause skin and eye irritation; should be handled with appropriate safety measures

InChI:InChI=1/C10H9NS/c11-10-8-4-2-1-3-7(8)5-6-9(10)12/h1-6,12H,11H2

Upstream product

• 86-88-4 naphthalen-1-yl-thiourea 
• 134-32-7 1-amino-naphthalene 
• 96963-35-8 [2,2']bi[naphtho[1,2-d]thiazolyl] 
• 72142-85-9 2-Phenyl-naphtho<1,2-d>thiazol 
• 4845-64-1 1H-naphtho[1,2-d]thiazole-2-thione 
• 40172-65-4 SKA-31 

Downstream Products

• 136928-65-9 3-(4-chlorophenyl)-1H-naphtho-[2,1-b][1,4]thiazin-2(3H)-one 
• 1231747-40-2 1-methyl-cyclohexanecarbothioic acid S-{1-[(1-methyl-cyclohexanecarbonyl)-amino]-naphthalen-2-yl}ester 
• 52-67-5 3,3-dimethyl-D-cysteine 
• 139331-56-9 3-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-1H-naphtho[2,1-b][1,4]thiazin-2-one 
• 2682-45-3 2-methylnaphtho[1,2-d]thiazole 
• 38262-57-6 2,2'-dithiobis-(1-aminonaphtalene) 

Relevant articles and documents

Structure determination from powder X-ray diffraction data of black azo (hydrazone) pigments

Crystal structures of two black monoazo (hydrazone) pigments have been determined from powder X-ray diffraction data combined with DFT calculations. The DFT calculations suggested the molecules are in hydrazone forms but not in azo forms in both crystal structures. The molecular arrangements in the crystal structures suggested Davydov splitting may occur by excitonic interactions and it causes the red absorption band shift in the crystalline state leading to the characteristic black colors.

Synthesis and biological activities of new 1,4-benzothiazine derivatives

New 2H-1,4-benzothiazin-3(4H)-one derivatives possessing (4-phenyl-1-piperazinyl)alkyl moieties at the 2-position were synthesized and tested for calcium antagonistic and calmodulin antagonistic activities. Antihypertensive effects in spontaneously hypertensive rats were also evaluated. In general, these compounds were rather weak calcium channel blockers, although, in contrast, many of them had moderate to potent calmodulin antagonistic activity, and 2-[3-(4-(4-fluorophenyl)-1-piperazinyl]propyl]-2H-1,4-benzothiazin-3(4H )-one derivatives 45, 74 and 75 showed potent antihypertensive effects.