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(1S,4S)-7-(tert-butoxycarbonyl)-7-azabicyclo[2.2.1]hept-5-en-2-one is a bicyclic compound with the molecular formula C11H15NO3. It features a lactam ring and a tert-butoxycarbonyl (Boc) protecting group, and it possesses a specific (1S,4S) stereochemistry. (1S,4S)-7-(tert-butoxycarbonyl)-7-azabicyclo[2.2.1]hept-5-en-2-one is utilized in organic synthesis for constructing complex molecules and serves as a starting material for pharmaceutical synthesis. The Boc group can be removed under mild acidic conditions, which is advantageous for protecting amino groups during organic synthesis processes.

635298-68-9

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635298-68-9 Usage

Uses

Used in Organic Synthesis:
(1S,4S)-7-(tert-butoxycarbonyl)-7-azabicyclo[2.2.1]hept-5-en-2-one is used as a building block in organic synthesis for creating complex molecules due to its unique bicyclic structure and Boc protecting group.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (1S,4S)-7-(tert-butoxycarbonyl)-7-azabicyclo[2.2.1]hept-5-en-2-one is used as a starting material for the synthesis of various pharmaceuticals. Its ability to protect amino groups with the Boc group makes it a valuable intermediate in the development of new drugs.
Used in Chemical Research:
(1S,4S)-7-(tert-butoxycarbonyl)-7-azabicyclo[2.2.1]hept-5-en-2-one is also utilized in chemical research for studying the properties and reactions of bicyclic compounds and their potential applications in various chemical processes.

Check Digit Verification of cas no

The CAS Registry Mumber 635298-68-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,5,2,9 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 635298-68:
(8*6)+(7*3)+(6*5)+(5*2)+(4*9)+(3*8)+(2*6)+(1*8)=189
189 % 10 = 9
So 635298-68-9 is a valid CAS Registry Number.

635298-68-9Relevant academic research and scientific papers

Efficient resolution of N-Boc-7-azabicyclo[2.2.1]hept-5-en-2-one: Formal syntheses of natural epibatidine and its enantiomer

Moreno-Vargas, Antonio J.,Vogel, Pierre

, p. 3173 - 3176 (2003)

The efficient resolution of racemic N-Boc-7-azabicyclo[2.2.1]hept-5-en-2- one (±)-2 via aminal formation with (R,R)-1,2-diphenylethylenediamine 4 is reported. Acidic hydrolysis furnishes the enantiomeric ketones (+)-2 and (-)-2 that were transformed into 7-azabicyclo[2.2.1]heptan-2-one (-)-3 and (+)-3. The process constitutes a formal synthesis of (+)- and (-)-epibatidine.

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