635311-75-0Relevant academic research and scientific papers
Potent, selective and low-calcemic inhibitors of CYP24 Hydroxylase: 24-Sulfoximine analogues of the hormone 1α,25-dihydroxyvitamin D 3
Kahraman, Mehmet,Sinishtaj, Sandra,Dolan, Patrick M.,Kensler, Thomas W.,Peleg, Sara,Saha, Uttam,Chuang, Samuel S.,Bernstein, Galina,Korczak, Bozena,Posner, Gary H.
, p. 6854 - 6863 (2007/10/03)
A dozen 24-sulfoximine analogues of the hormone 1α,25- dihydroxyvitamin D3 were prepared, differing not only at the stereogenic sulfoximine stereocenter but also at the A-ring. Although these sulfoximines were not active transcriptionally and w
24-SULFOXIMINE VITAMIN D3 COMPOUNDS
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Page 50-52, (2010/11/30)
The present invention provides novel sulfoximine compounds, compositions comprising these compounds and methods of using these compounds as inhibitors of CYP24. In particular, the compounds of the invention are useful for treating diseases which benefit f
