635316-98-2Relevant academic research and scientific papers
Synthesis of an octamannosyled glycan chain, the key oligosaccharide structure in ER-associated degradation
Matsuo, Ichiro,Ito, Yukishige
, p. 2163 - 2168 (2003)
The high-mannose type decasaccharide (Man8GlcNAc2), the proposed ligand of ER residing mannosidase-like proteins (MLP), and its monoglycosylated homologue (α-Glc1Man8GlcNAc 2) were synthesized. The oligosaccharide assembly was performed in a convergent and stereoselective manner, using three oligosaccharide components, a core trisaccharide having a β-mannoside bond, a liner mannotriose, and a branched mannotetraose.
