635325-97-2Relevant academic research and scientific papers
Integration of Enzymatic and Heterogeneous Catalysis for One-Pot Production of Fructose from Glucose
Sun, Jiankui,Li, Helong,Huang, Hongzhi,Wang, Bo,Xiao, Ling-Ping,Song, Guoyong
, p. 1157 - 1162 (2018/03/21)
The search for efficient routes for the production of fructose from biomass-derived glucose is of great interest and importance, as fructose is a highly attractive substrate in the conversion of cellulosic biomass into biofuels and chemicals. In this study, a one-pot, multistep procedure involving enzyme-catalyzed oxidation of glucose at C2 and Ni/C-catalyzed hydrogenation of d-glucosone at C1 selectively gives fructose in 77 % yield. Starting from upstream substrates such as α-cellulose and starch, fructose was also generated with similar efficiency and selectivity by the combination of enzymatic and heterogeneous catalysis. This method constitutes a new means of preparing fructose from biomass-derived substrates in an efficient fashion.
