63559-21-7

Basic information

• Product Name: 1,2-Benzenedicarboxylic acid, 5-hydroxy-3-methyl-, dimethyl ester
• CAS NO: 63559-21-7
• Molecular Formula: C11H12O5
• Molecular Weight: 224.213
• Mol File: 63559-21-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,2-Benzenedicarboxylic acid, 5-hydroxy-3-methyl-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenedicarboxylic acid, 5-hydroxy-3-methyl-, dimethyl ester(63559-21-7)
• EPA Substance Registry System: 1,2-Benzenedicarboxylic acid, 5-hydroxy-3-methyl-, dimethyl ester(63559-21-7)

Safety Data

• Hazardous Substances Data: 63559-21-7(Hazardous Substances Data)

Usage

Usage

Plasticizer in industrial and consumer products

Applications

Adhesives, sealants, vinyl flooring, resins, and polymers

Function

Increases flexibility and durability of materials

Benefits

Enhanced resistance to heat and chemicals

Health concerns

Potential endocrine disruptor

Regulatory status

Restrictions imposed by some regulatory bodies in certain applications

Upstream product

• 18064-04-5 dimethyl 1-methyl-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate 
• 108298-55-1 3-Methyl-5-(trimethylsiloxy)phthalsaeure-dimethylester 
• 63446-76-4 1-methyl-1,3-bis(trimethylsilyloxy)buta-1,3-diene 
• 762-42-5 dimethyl acetylenedicarboxylate 

Relevant articles and documents

Rhodium-catalyzed asymmetric cyclodimerization of oxabenzonorbornadienes and azabenzonorbornadienes: Scope and limitations

(Chemical Equation Presented) Cationic rhodium(I)-catalyzed cyclodimerization of oxabenzonorbornadienes produced naphtho[1,2-b]-furan ring systems in a single step with excellent yields and excellent enantioselectivities. The effect of various Rh(I) catalysts, Ag(I) salts, solvents, and phosphine ligands on the yield and enantioselectivity of the reaction was investigated, and the scope and limitations of this reaction with various oxabicyclic alkenes were studied. Similar results were obtained with the azabenzonorbornadiene analogues, providing the corresponding cyclodimerization products in excellent yields and excellent enantioselectivities.

Syntheses of Highly Substituted Benzenes via Diels-Alder Reactions with 2H-Pyran-2-ones

The 2H-pyran-2-ones (α-pyrones) 1 react as dienes in Diels-Alder reactions with acetylene derivatives.The primarely formed cycloadducts immediately aromatize to benzenes by CO2 elimination.Thus, methyl acetylenedicarboxylate (2a) gives dimethyl phthalates 3, and methyl acetylenediphosphonate (2b) gives dimethyl 1,2-phenylenediphosphonates 8.The reactions of 1-(dimethylamino)-1-methoxyethene (9) with 1 regioselectively produce N,N-dimethylanilines 10 and isomeric homophthalate derivatives 12.Naphthoquinones 14 could be generated from 1,4-benzoquinone (13) and 1 in the presence of acetic anhydride and Pd/C.Hydroxy-2H-pyran-2-ones 4 react via their trimethylsilyl ether 6 analogously with 2a to give dimethyl (trimethylsiloxy)phthalates 7 which are easily converted to phenols 5 by acid-catalyzed hydrolysis.