63564-39-6

Basic information

• Product Name: Benzaldehyde, 4-chloro-, O-(2-hydroxyethyl)oxime, (E)-
• CAS NO: 63564-39-6
• Molecular Formula: C9H10ClNO2
• Molecular Weight: 199.637
• Mol File: 63564-39-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 4-chloro-, O-(2-hydroxyethyl)oxime, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 4-chloro-, O-(2-hydroxyethyl)oxime, (E)-(63564-39-6)
• EPA Substance Registry System: Benzaldehyde, 4-chloro-, O-(2-hydroxyethyl)oxime, (E)-(63564-39-6)

Safety Data

• Hazardous Substances Data: 63564-39-6(Hazardous Substances Data)

Upstream product

• 3279-95-6 O-(2-hydroxyethyl)hydroxylamine 
• 104-88-1 4-chlorobenzaldehyde 

Relevant articles and documents

Oxime ether derivatives, a new class of nonsteroidal antiinflammatory compounds

A series of new 2-hydroxyethyl and carboxyalkyl ethers of aromatic oximes was found to possess pronounced antiinflammatory activity in the carrageenan-induced edema test in the rat. The activity was limited mainly to derivatives of p-haloacetophenone oxime and of p-halobenzaldehyde oxime. Nevertheless the hydroxyethyl and carboxyalkyl groups may be converted into many derivatives with maintenance of activity. Some structure-activity relationships are in contrast to those of the well-known antiinflammatory arylacetic acids. The activity is limited to the E stereoisomers. The hydrochloride of 2-(dimethylamino)ethyl (E)-[[(p-chloro-α- methylbenzylidene)-amino]oxy]acetate (36, INN name Cloximate) was cosen for clinical evaluation. The first results agree with the pharmacological prospects.