635678-91-0

Upstream product

• 180591-23-5 (2S,3R)-3-[(4S,5R)-5-((R)-1-Hydroxy-2-trityloxy-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-oxirane-2-carboxylic acid diethylamide 
• 100-46-9 benzylamine 
• 635678-88-5 Methanesulfonic acid (R)-1-[(4S,5S)-5-((2R,3S)-3-diethylcarbamoyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-2-trityloxy-ethyl ester 

Relevant academic research and scientific papers

Iminosugars from α,β-epoxyamides. Part 1: Synthetic approach to hydroxylated piperidine derivatives

A new synthetic route towards iminosugars starting from chiral epoxyamides is described. The strategy, by which a single precursor, the α,β-epoxyamide obtained from 6-O-trityl-2, 3-O-isopropylidene-D-ribose and a sulphur ylide, can be transformed into different iminosugars, is based on the combination of a regioselective epoxide opening and stereospecific intramolecular displacements.