63598-34-5Relevant academic research and scientific papers
Synthesis of spacer-linked tail to tail dimers derived from a conformationally rigid aminodeoxysugar by olefin metathesis
Kirschning, Andreas,Chen, Guang-Wu
, p. 1133 - 1137 (2007/10/03)
The preparation of new tail to tail dimers of bridged aminodeoxysugars 2 and 11 is described. The first key step in the synthesis is the formation of the aminomethyl bridge in the carbohydrate-derived monomer 7 which is achieved by silver promoted ring closure of methyl 3-acetamido-6-bromo-2,3,6- trideoxy α-D-glucoside 6. Secondly, olefin metathesis of the corresponding 4-O-allyl glycoside 9 constitutes a powerful tool for dimerization, which allows synthesis of 1,4-butanediol-linked tail to tail neooligosaccharides 2 and 11.
The Deoxygenation of some Derivatives of Methyl 3-Amino-3-deoxy-α-D-glucopyranoside
Patroni, Joseph J.,Stick, Robert V.
, p. 947 - 952 (2007/10/02)
The deoxygenation, at C2, of methyl 3-acetylamino-4,6-O-benzylidene-3-deoxy-α-D-glucoside, is described, and the subsequent conversion of the product into 3-acetylamino-2,3-dideoxy-D-arabino-hexose.Attempts at further deoxygenation (at C6), even the use of trifluoroacetylamino derivatives, were unsuccessful.
