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5-[(2-hydroxyphenyl)methylidene]-2-thioxoimidazolidin-4-one is a complex organic compound with the molecular formula C10H7NOS2. It is characterized by a 2-thioxoimidazolidin-4-one core structure, which features a five-membered ring with a sulfur atom at the 2-position and a carbonyl group at the 4-position. The compound is further defined by a 2-hydroxyphenyl group attached to the 5-position of the imidazolidinone ring through a methylene bridge. This molecule is known for its potential applications in pharmaceuticals and chemistry, particularly as a precursor or intermediate in the synthesis of various biologically active compounds. Its structure provides a foundation for further functionalization and exploration of its properties in different chemical and biological contexts.

636-86-2

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636-86-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 636-86-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,3 and 6 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 636-86:
(5*6)+(4*3)+(3*6)+(2*8)+(1*6)=82
82 % 10 = 2
So 636-86-2 is a valid CAS Registry Number.

636-86-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-(2-HYDROXYBENZYLIDENE)-2-THIOHYDANTOIN

1.2 Other means of identification

Product number -
Other names 5-Salicyliden-2-thioxo-imidazolidin-4-on

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:636-86-2 SDS

636-86-2Downstream Products

636-86-2Relevant academic research and scientific papers

New compounds having skin whitening, antioxidant and PPAR activity, and medical use thereof

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Paragraph 0379-0380; 0400, (2017/04/14)

PURPOSE: A novel compound with skin whitening, antioxidation, and PPAR activation effects, and a medical use thereof are provided to be used for a pharmaceutical composition or a cosmetic product. CONSTITUTION: A compound is denoted by chemical formula 1. A skin whitening composition contains the compound as an active ingredient. An antioxidative composition for preventing or treating oxidative diseases contains the compound of chemical formula 1 as an active ingredient. The oxidative diseases are selected among skin aging, pigmentation, wrinkling, psoriasis, or eczema. The composition prevents or treats diseases which are regulated by PPAR(peroxisome proliferator-activated receptor) activity. The PPAR includes PPAR alpha or PPAR gamma.

Benzylidene-linked thiohydantoin derivatives as inhibitors of tyrosinase and melanogenesis: Importance of the β-phenyl-α,β-unsaturated carbonyl functionality

Kim, Hye Rim,Lee, Hye Jin,Choi, Yeon Ja,Park, Yun Jung,Woo, Youngwoo,Kim, Seong Jin,Park, Min Hi,Lee, Hee Won,Chun, Pusoon,Chung, Hae Young,Moon, Hyung Ryong

, p. 1410 - 1417 (2014/10/15)

Based on the structural characteristics of the heterocyclic scaffolds of substituted benzylidene-hydantoin, -pyrrolidinedione, and -thiazolidinedione derivatives with potent tyrosinase inhibitory activity, substituted benzylidene derivatives with a 2-thio

NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR

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Paragraph 0252; 0253; 0263, (2014/02/16)

Provided are a novel compound having skin-whitening, anti-oxidizing and PPAR activities and a medical use thereof, and the compound has skin-whitening activities for the suppression of tyrosinase, and accordingly, is useful for use in skin-whitening pharmaceutical composition or cosmetic products; has anti-oxidant activities, and accordingly, is useful for the prevention and treatment of skin-aging; and has PPAR activities, and in particular, PPARα and PPARγ activities, and accordingly, is useful for use in pharmaceutical compositions or health foods which are effective for the prevention and treatment of obesity, metabolic disease, or cardiovascular disease.

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