6363-00-4Relevant articles and documents
A kind of leptine-containing brain-targeted nano-preparation and preparation method thereof
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Paragraph 0044-0046; 0049, (2022/03/27)
The present invention discloses a brain-targeted nanopharmacene containing hookerine, which is a nuclear material with 60% - γ-PFGA as a core shell structure nanoparticle, a shell material with a core shell structure nanoparticles in PLA-SS-PEG-A2, a nano-formulation with a core shell structure prepared by E-TPGS as a nonionic surfactant, a nano-preparation with a core shell structure prepared by loading hook vine alkali or at the same time supporting hook vine alkali and Tariquidar. Brain targeting nanopharmaceuticals containing hookerine containing hook vine are small in size, structurally stable, have sustained release and controlled release effects, overcome the difficulty of low encapsulation rate of hook vine alkali, and improve the brain targeting of hook vine base.
Thiocarbonyl Surrogate via Combination of Potassium Sulfide and Chloroform for Dithiocarbamate Construction
Tan, Wei,J?nsch, Niklas,?hlmann, Tina,Meyer-Almes, Franz-Josef,Jiang, Xuefeng
supporting information, p. 7484 - 7488 (2019/10/08)
An efficient and practical thiocarbonyl surrogate via combination of potassium sulfide and chloroform was established. A variety of dithiocarbamates were afforded along with four new chemical bond formations in a one-pot reaction in which the thiocarbonyl
Deep eutectic mixture catalysed the synthesis of disulfides using Bunte salts as thiol surrogates
Zhou, Yongsheng
, p. 332 - 335 (2015/08/18)
Bunte salts, easily prepared from odourless sodium thiosulfates and various alkyl and aryl halides, acted as thiol surrogates for preparation of disulfides in the presence of hydrogen peroxide and a Bronsted-acidic deep eutectic mixture. The reaction proceeded smoothly to give the corresponding disulfide products in moderate to good yields, leaving odourless sodium bisulfite and water as the by-products. Moreover, this catalytic system could be readily recovered and reused several times without significant loss in activity.