63636-89-5

Basic information

• Product Name: 2-Pyridinesulfonamide(6CI,7CI,9CI)
• Synonyms: 2-Pyridinesulfonamide(6CI,7CI,9CI);pyridine-2-sulfonic acid amide;pyridine-2-sulfonamide;Pyridine -2-suflonly aMide
• CAS NO: 63636-89-5
• Molecular Formula: C₅H₆N₂O₂S
• Molecular Weight: 158.18
• EINECS: 201-525-2
• Product Categories: SULFONAMIDE;Pyridine
• Mol File: 63636-89-5.mol
• Article Data: 13

Chemical Properties

• Melting Point: 140-141 °C(Solv: ethanol (64-17-5); water (7732-18-5))
• Boiling Point: 357.711 °C at 760 mmHg
• Flash Point: 170.138 °C
• Appearance: /
• Density: 1.417 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.577
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 9.21±0.60(Predicted)
• CAS DataBase Reference: 2-Pyridinesulfonamide(6CI,7CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinesulfonamide(6CI,7CI,9CI)(63636-89-5)
• EPA Substance Registry System: 2-Pyridinesulfonamide(6CI,7CI,9CI)(63636-89-5)

Safety Data

• Hazardous Substances Data: 63636-89-5(Hazardous Substances Data)

Usage

General Description

2-Pyridinesulfonamide(6CI,7CI,9CI) is a chemical compound with the molecular formula C5H6N2O2S. It is a derivative of pyridine and contains a sulfonamide group. 2-Pyridinesulfonamide(6CI,7CI,9CI) has various uses in the pharmaceutical and chemical industries, including as a building block in the synthesis of other chemical compounds. It can also be used as a reagent in organic synthesis reactions. 2-Pyridinesulfonamide has potential applications in medicinal chemistry due to its ability to act as a ligand for metal ions and as a potential pharmacophore in drug discovery. Further research and studies may reveal additional potential uses and properties of this compound.

InChI:InChI=1/C5H6N2O2S/c6-10(8,9)5-3-1-2-4-7-5/h1-4H,(H2,6,8,9)

Upstream product

• 99780-72-0 3-mercaptopyridin-2-ylsulfonamide 
• 352-91-0 1-Bromo-3-fluoropropane 
• 109-04-6 2-bromo-pyridine 
• 81745-83-7 pyridin-2-ylzinc(ll) bromide 
• 13939-06-5 molybdenum hexacarbonyl 
• 2127-03-9 2,2'-dipyridyldisulphide 
• 16133-25-8 Pyridine-3-sulfonyl chloride 
• 2637-34-5 2-Sulfanylpyridine 
• 66715-65-9 pyridine-2-sulfonyl chloride 

Downstream Products

• 19009-75-7 2-Pyridin-sulfonamid-1-oxid 
• 243467-03-0 C₁₁H₉IN₂O₂S 
• 415906-47-7 2-ethyl-3-(4-{2-[({[2-pyridinylsulfonyl]amino}carbonyl)amino]ethyl}phenyl)-5,7-dimethyl-3H-imidazo[4,5-b]pyridine 
• 1029585-25-8 N-[(3-methoxyphenyl)methylidene]-2-pyridinesulfonamide 
• 872874-17-4 (E)-phenyl-N-(2-pyridylsulfonyl)methanimine 
• 128577-41-3 2-Cyclopentyl-N-{1-[2-methoxy-4-(pyridine-2-sulfonylaminocarbonyl)-benzyl]-1H-indol-6-yl}-acetamide 
• 880470-15-5 (2,4,6-trimethoxyphenyl)(phenyl)-N-[(2-pyridyl)sulfonyl]methanamine 
• 880470-14-4 (1-methoxy-2-naphthyl)(phenyl)-N-[(2-pyridyl)sulfonyl]methanamine 

Relevant articles and documents

2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain 2-amino-N-(amino-oxo-aryl-λ6- sulfanylidene)acetamide compounds (referred to herein as ANASIA compounds) that, inter alia, inhibit (e.g., selectively inhibit) bacterial aminoacyl-tRNA synthetase (aaRS) (e.g., bacterial leucyl-tRNA synthetase, LeuRS). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit (e.g., selectively inhibit) bacterial aminoacyl-tRNA synthetase; to treat disorders that are ameliorated by the inhibition (e.g., selective inhibition) of bacterial aminoacyl-tRNA synthetase; to treat bacterial infections; etc.

Fe(III)/ l -Valine-Catalyzed One-Pot Synthesis of N -Sulfinyl- and N -Sulfonylimines via Oxidative Cascade Reaction of Alcohols with Sulfinamides or Sulfonamides

An efficient Fe(III), l -valine, and 4-OH-TEMPO catalytic system was found for the oxidation of alcohols followed by condensation with sulfinamide or sulfonamide in one pot for the synthesis of N -sulfinyl- and N- sulfonylimines compounds under mild conditions. This transformation accommodates a variety of substrates, shows high functional-group tolerance, and affords the corresponding products in good to excellent yields.

SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME

ABSTRACT The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.