6364-00-7 Usage
General Description
N-(4-ethoxyphenyl)naphthalen-1-amine is a chemical compound that consists of a naphthalene ring attached to an amine group and an ethoxyphenyl substituent. It is commonly used in organic synthesis and pharmaceutical research due to its potential pharmacological properties. N-(4-ethoxyphenyl)naphthalen-1-amine may be utilized in the development of new drugs and pharmaceuticals for various medical conditions. Its unique molecular structure and properties make it a valuable tool in the field of medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 6364-00-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,6 and 4 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6364-00:
(6*6)+(5*3)+(4*6)+(3*4)+(2*0)+(1*0)=87
87 % 10 = 7
So 6364-00-7 is a valid CAS Registry Number.
InChI:InChI=1/C18H17NO/c1-2-20-16-12-10-15(11-13-16)19-18-9-5-7-14-6-3-4-8-17(14)18/h3-13,19H,2H2,1H3
6364-00-7Relevant articles and documents
NIXANTPHOS: A highly active ligand for palladium catalyzed Buchwald-Hartwig amination of unactivated aryl chlorides
Mao, Jianyou,Zhang, Jiadi,Zhang, Shuguang,Walsh, Patrick J.
supporting information, p. 8690 - 8696 (2018/07/13)
Xantphos is one of the two most common ligands used in palladium catalyzed Buchwald-Hartwig amination reactions, because of its broad scope and high probability of success. It does not, however, work well with unactivated aryl chlorides. Herein NIXANTPHOS is compared to Xantphos and an array of mono- and bidentate phosphines. NIXANTPHOS outperforms Xantphos and all other bidentate ligands examined. Under the optimal reaction conditions, unactivated aryl chlorides afford the expected products in good to excellent yield with as low as 0.05 mol% (500 ppm) palladium loading.
