63645-51-2Relevant academic research and scientific papers
The Preparation of 5-Phenacylisoxazoles and 5-Hydroxyphenylisoxazoles and -pyrazoles by the Condensation of C(α)-Dianions with Ethyl Benzoylacetate and Methyl Salicylate
Livingston, Melanie J.,Chick, MarLisa F.,Shealy, Ernest O.,Beam, Charles F.
, p. 215 - 217 (2007/10/02)
C(α),O-Dilithiooximes and C(α),N-Dilithiophenylhydrazones were prepared in an excess of lithium diisopropylamide (LDA).The former was condensed with ethyl benzoylacetate and methyl salicylate, and the latter condensed with methyl salicylate.The resulting precyclization intermediates were than treated with aqueous acid, which was followed by cyclodehydration to give phenacylisoxazoles and hydroxyphenylisoxazoles and -pyrazoles.
CHALCONE OXIMES. PART V. REACTION OF HYDROXYLAMINE WITH 4-SUBSTITUTED 2'-HYDROXYCHALCONES
Witczak, Zbigniew,Krolikowska, Maria
, p. 89 - 100 (2007/10/02)
The reactions of hydroxylamine with 4-substituted 2'-hydroxychalcones have been investigated.Formation of products of 1,2 addition and simultaneous 1,4 and 1,2 addition for R = -CH3, -Cl have been established.Products of 1,2 addition for R = -OCH3 and of
REACTION OF HYDROXYLAMINE WITH 4'-SUBSTITUTED FLAVONE DERIVATIVES
Witczak, Zbigniew,Krolikowska, Maria
, p. 763 - 773 (2007/10/02)
Reactions of hydroxylamine with 4'-substituted flavones have been investigated.Formation of oxime flavone and isoxazole for R = -OCH3, -CH3, -Cl and only isoxazole for R = -OH has been stated, whereas for R = -NO2 formation of an intermediate product of opening γ-pyrone ring and both isomeric isoxazoles has been observed.
