63646-52-6Relevant academic research and scientific papers
A counteranion triggered arylation strategy using diaryliodonium fluorides
Chan,McNally,Toh,Mendoza,Gaunt
, p. 1277 - 1281 (2015)
A mild and transition metal-free counteranion triggered arylation strategy has been developed using diaryliodonium fluorides. The fluoride counteranion within the hypervalent iodonium species displays unusual reactivity that activates a phenolic O-H bond leading to electrophilic O-arylation. A wide range of phenols and diaryliodonium salts are compatible with this transformation under remarkably mild conditions. Furthermore, we pre-empt the wider implications of this strategy by demonstrating the compatibility of the arylation tactic with latent carbon nucleophiles.
