63656-59-7Relevant academic research and scientific papers
Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors
Zhou, Du-Chao,Lu, Yu-Ting,Mai, Yan-Wen,Zhang, Chen,Xia, Jie,Yao, Pei-Fen,Wang, Hong-Gen,Huang, Shi-Liang,Huang, Zhi-Shu
, (2019/08/06)
For the development of novel anticancer agents, we designed and synthesized a total of 37 perimidine o-quinone derivatives containing the o-quinone group at the A or B ring and different substituents (alkyl groups, aryl groups or heterocycles) at the C ri
