63659-19-8 Usage
Description
Different sources of media describe the Description of 63659-19-8 differently. You can refer to the following data:
1. Betaxolol hydrochloride is a cardioselective β-adrenergic blocker, reportedly devoid
of intrinsic sympathomimetic and membrane stabilizing properties. Its long
duration of action permits once-daily dosing in mild to moderate hypertension. It
is also being evaluated in glaucoma.
2. Betaxolol (hydrochloride) (Item No. 26285) is an analytical reference standard categorized as a β1-adrenergic receptor antagonist. Formulations containing β-adrenergic receptor antagonists have been used to enhance physical performance in athletes. This product is intended for use in analytical forensic applications. This product is also available as a general research tool .
Chemical Properties
White or almost white, crystalline powder.
Originator
Synthelabo (France)
Uses
Different sources of media describe the Uses of 63659-19-8 differently. You can refer to the following data:
1. Betaxolol Hydrochloride, a cardioselective β1-adrenergic blocker. An antihypertensive; antiglaucoma.
2. antifungal
Definition
ChEBI: The hydrochloride salt of betaxolol.
Biological Activity
Selective β 1 -adrenoceptor antagonist.
Check Digit Verification of cas no
The CAS Registry Mumber 63659-19-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,6,5 and 9 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 63659-19:
(7*6)+(6*3)+(5*6)+(4*5)+(3*9)+(2*1)+(1*9)=148
148 % 10 = 8
So 63659-19-8 is a valid CAS Registry Number.
InChI:InChI=1/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H
63659-19-8Relevant articles and documents
COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING SALT SENSITIVITY OF BLOOD PRESSURE
-
, (2015/02/05)
To characterize the urinary exosome miRNome, microarrays were used to identify the miRNA spectrum present within urinary exosomes from ten individuals that were previously classified for their salt sensitivity status. The present application discloses distinct patterns of selected exosomal miRNA expression that were different between salt-sensitive (SS), salt-resistant (SR), and inverse salt-sensitive (ISS) individuals. These miRNAs can be useful as biomarkers either individually or as panels comprising multiple miRNAs. The present invention provides compositions and methods for identifying, diagnosing, monitoring, and treating subjects with salt sensitivity of blood pressure. The applications discloses panels of miRNAs useful for comparing profiles, and in some cases one or more of the miRNAs in a panel can be used. The miRNAs useful for distinguishing SS and SR or ISS and SR subjects. One or more of the 45 miRNAs can be used. Some of the miRNAs have not been previously reported to be circulating. See those miRNAs with asterisks in FIG. 1 and below. The present invention encompasses the use of one or more of these markers for identifying and diagnosing SR, SS, and ISS subjects.
Process for the selective alkylation of betaxolol intermediates
-
, (2008/06/13)
The present invention relates to a process for the selective alkylation of intermediates of betaxolol.
