63659-65-4

Upstream product

• 63659-64-3 4-<<(cyclobutylmethyl)sulfonyl>ethyl>phenol 
• 3132-64-7 1,2-Epoxy-3-bromopropane 
• 13295-53-9 cyclobutylmethyl 4-methylbenzenesulfonate 
• 63659-59-6 2-(4-methoxyphenyl)ethyl mercaptan 
• 14425-64-0 4-methoxyphenethyl bromide 
• 106-89-8 epichlorohydrin 
• 63659-63-2 4-<<(cyclobutylmethyl)sulfonyl>ethyl>-1-methoxybenzene 
• 63659-60-9 4-(2-cyclobutylmethylthio-ethyl)-1-methoxy-benzene 

Downstream Products

• 63659-66-5 1-[4-(2-Cyclobutylmethylsulphonyl-ethyl)phenoxy]-3-isopropylamino-propan-2-ol 

Relevant academic research and scientific papers

PHENOL ETHERS

The invention provides phenol ethers of the formula: STR1 wherein R is branched C 3-4 alkyl, C 3-4 cycloalkyl, branched cyano(C 3-4 alkyl), phenyl(C 2-3 alkyl), halophenyl(C 2-3 alkyl), (C 1-4 alkoxy)phenyl(C 2-4 alkyl), or (C 1-4 acyl) amino(C 1-4 alkyl),alk is C 1-4 alkyl substituted by a 3 to 6 membered cycloalkyl group,X is--O--,--S--or--SO 2--; andR 1 is--C 1-4 alkyl-or--C 1-4 alkoxy-, in their racemic and optically active forms, and their addition salts with pharmaceutically acceptable acids. These compounds are useful in therapy as β-adrenergic blocking agents. Intermediates are also provided.