63659-85-8

Basic information

• Product Name: 3-(4-FLUORO-PHENYL)-1-METHYL-PROPYLAMINE
• Synonyms: 3-(4-FLUORO-PHENYL)-1-METHYL-PROPYLAMINE;TIMTEC-BB SBB010486
• CAS NO: 63659-85-8
• Molecular Formula: C₁₀H₁₄FN
• Molecular Weight: 167.22
• Mol File: 63659-85-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-FLUORO-PHENYL)-1-METHYL-PROPYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-FLUORO-PHENYL)-1-METHYL-PROPYLAMINE(63659-85-8)
• EPA Substance Registry System: 3-(4-FLUORO-PHENYL)-1-METHYL-PROPYLAMINE(63659-85-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 63659-85-8(Hazardous Substances Data)

Usage

Uses

3-(4-Fluoro-phenyl)-1-methyl-propylamine can be used as herbicides and plant growth regulators.

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 65300-29-0 4-(4-fluorophenyl)but-3-en-2-one 
• 352-11-4 1-chloromethyl-4-fluorobenzene 
• 88023-07-8 ethyl 2-<(4-fluorophenyl)methyl>-3-oxobutanoate 
• 63416-61-5 4-(4-fluorophenyl)-2-butanone 

Downstream Products

• 63659-73-4 1-[4-(2-Cyclobutylmethoxy-ethyl)-phenoxy]-3-[3-(4-fluoro-phenyl)-1-methyl-propylamino]-propan-2-ol 

Relevant articles and documents

8-Hydroxyquinolin-2(1H)-one analogues as potential β2-agonists: Design, synthesis and activity study

β2-Agonists that bind to plasmalemmal β2-adrenoceptors causing cAMP accumulation are widely used as bronchodilators in chronic respiratory diseases. Here, we designed and synthesized a group of 8-hydroxyquinolin-2(1H)-one analogues and studied their β2-agonistic activities with a cellular cAMP assay. Compounds B05 and C08 were identified as potent (EC50 2-agonists among the compounds tested. They behaved as partial β2-agonists in non-overexpressed HEK293 cells, and possessed rapid smooth muscle relaxant actions and long duration of action in isolated guinea pig tracheal strip preparations. In summary, B05 and C08 are β2-agonists with potential applicability in chronic respiratory diseases.