6366-28-5Relevant academic research and scientific papers
Base-controlled selective conversion of Michael adducts of malonates with enones in the presence of iodine
Miao, Chun-Bao,Zhang, Min,Tian, Zong-Yong,Xi, Hai-Tao,Sun, Xiao-Qiang,Yang, Hai-Tao
experimental part, p. 9809 - 9816 (2012/01/06)
An efficient base-controlled selective conversion of the Michael adducts of malonates with enones in the presence of iodine is reported. Highly functionalized cyclopropane, oxetane, and α-hydroxylmalonate derivatives are obtained selectively using DBU, Na2CO3, and NaOAc as the base, respectively. O2 was identified to be crucial to the formation of oxetane and α-hydroxylmalonate derivatives.
