63674-65-7 Usage
Uses
Used in Pharmaceutical Industry:
1-(3,4-DIMETHYLPHENYL)-2-OXOPYRROLIDINE-4-CARBOXYLIC ACID is used as a building block and intermediate for the synthesis of various pharmaceutical drugs, leveraging its chemical properties to contribute to the development of new medications.
Used in Antibacterial Applications:
In the field of microbiology, 1-(3,4-DIMETHYLPHENYL)-2-OXOPYRROLIDINE-4-CARBOXYLIC ACID is used for its potential antibacterial properties, offering a possible solution in combating bacterial infections.
Used in Antifungal Applications:
Similarly, 1-(3,4-DIMETHYLPHENYL)-2-OXOPYRROLIDINE-4-CARBOXYLIC ACID is utilized for its antifungal capabilities, providing a means to address fungal infections and related conditions.
Used in Anticancer Applications:
1-(3,4-DIMETHYLPHENYL)-2-OXOPYRROLIDINE-4-CARBOXYLIC ACID is also being explored for its potential role in cancer treatment, with research indicating that it may have applications in the management of certain types of cancer, thus offering hope for therapeutic advancements in oncology.
Check Digit Verification of cas no
The CAS Registry Mumber 63674-65-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,6,7 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 63674-65:
(7*6)+(6*3)+(5*6)+(4*7)+(3*4)+(2*6)+(1*5)=147
147 % 10 = 7
So 63674-65-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H15NO3/c1-8-3-4-11(5-9(8)2)14-7-10(13(16)17)6-12(14)15/h3-5,10H,6-7H2,1-2H3,(H,16,17)
63674-65-7Relevant academic research and scientific papers
COMPOUNDS AND USES THEREOF
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Page/Page column 90, (2018/05/17)
The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.
N-Aryl pyrrolidinonyl oxadiazoles as potent mGluR5 positive allosteric modulators
Packiarajan, Mathivanan,Mazza Ferreira, Christine G.,Hong, Sang-Phyo,White, Andrew D.,Chandrasena, Gamini,Pu, Xiaosui,Brodbeck, Robbin M.,Robichaud, Albert J.
scheme or table, p. 5658 - 5662 (2012/09/22)
A novel series of N-aryl pyrrolidinonyl oxadiazoles were identified as mGluR5 positive allosteric modulators (PAMs). Optimization of the initial lead compound 6a led to the identification of the 12c (-) enantiomer as a potent compound with acceptable in vitro clearance, CYP, hERG and PK properties. Para substituted N-aryl pyrrolidinonyl oxadiazoles are mGluR5 PAMs while the meta and ortho substituted N-aryl pyrrolidinonyl oxadiazoles are negative allosteric modulators (NAMs). Para fluoro substitution on the N-aryl group and meta chloro or methyl substituents on the aryl oxadiazole moiety are optimal for mGluR5 PAM efficacy. The existence of an exquisitely sensitive 'PAM to NAM switch' within this chemotype making it challenging for simultaneous optimization of potency and drug-like properties.
