637-45-6Relevant academic research and scientific papers
GREEN SYNTHESIS OF ARYL ALDIMINES USING ETHYL LACTATE
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Page/Page column 5-6, (2011/08/22)
The present invention relates to a method for preparing aryl aldimines. In particular, the present invention relates to methods of preparing aryl aldimines that uses environmentally friendly solvent systems.
Evaluation of N-(2-thienylidene)amines, N-(2-hydroxybenzylidene)amines and 3-iminoindolin-2-ones as antileishmanial agents
Al-Kahraman, Yasser M.S.A.,Singh, Girija S.,Yasinzai, Masoom
experimental part, p. 491 - 495 (2012/06/18)
The paper describes the synthesis and antileishmanial activity of N-substituted imines, obtained from the reactions of primary amines with three biologically important aldehydes/ketones, thiophene-2-carbaldehyde, 2- hydroxybenzaldehyde (salicylaldehyde) and indoline-2,3-dione. Of the fourteen compounds screened from three classes, five compounds showed significant antileishmanial activity. Among the three classes of imines, the class of N-(2- thienylidene)amines showed much better activity than the other two classes. N-(2-Thienylidene)benzhydrylamine showed IC50 value of 0.51 μg/ml. The effect of substituents on the bioactivity is discussed.
REACTIONS OF DICHLOROBIS(CYCLOPENTADIENYL)ZIRCONIUM(IV) WITH BIDENTATE SCHIFF BASES DERIVED FROM SALICYLALDEHYDE AND 4-SUBSTITUTED ANILINES
Sharma, A. K.,Khera, B.,Kaushik, N. K.
, p. 123 - 130 (2007/10/02)
Dichloro bis(cyclopentadienyl)zirconium(IV), Cp2ZrCl2, reacts with bidentate Schiff bases such as salicylidene-4-anisidine, salicylidene-4-phenetidine, salicylidene-4-chloroaniline, salicylidene-4-bromoaniline, salicylidene-4-iodoaniline and salicylidene-4-nitroaniline in a 1:1 molar ratio in refluxing tetrahydrofuran in the presence of triethylamine to yield Cp2Zr(SB)Cl, where (SB)- is the anion of the corresponding Schiff base, SBH.The new derivatives have been characterized on the basis of elemental analysis, molecular weight determination, conductance measurement and spectral (IR, 1H NMR) and electronic studies.
(Chloro)(N-arylsalicylaldiminato)bis(indenyl)titanium(IV) Compounds
Sharma, Anand,Khera, Brij,Kaushik, Narender K.
, p. 816 - 817 (2007/10/02)
Titanium(IV) complexes of the type (C9H7)2Ti(SB)Cl have been synthesised by the reaction of bis(indenyl)titanium(IV) dichloride and bidentate schiff base (SBH) in a 1:1 molar ratio in refluxing tetrahydrofuran in the presence of triethylamine.The new complexes have been characterised on the basis of their elemental analyses, conductance measurements and spectral (IR, 1H NMR and electronic) studies.
Bis(indenyl)zirkonium(IV) Complexes of Monofunctional Bidentate Salicylidimines
Sharma, A. K.,Khera, B.,Kaushik, N. K.
, p. 907 - 914 (2007/10/02)
A series of (C9H7)2Zr(SB)Cl complexes where SB(-) is the anion of bidentate Schiff base derived from salicylaldehyde and 4-substituted anilines, viz. salicylidene-4-anisidine, salicylidene-4-phenetidine, salicylidene-4-chloroaniline, salicylidene-4-bromoaniline, salicylidine-4-iodoaniline and salicylidine-4-nitroaniline, have been synthesized by the reaction of bis(indenyl)zirconium(IV)dichloride and Schiff base (SBH) in 1:1 molar ratio in refluxing THF in the presence of triethylamine.The new derivatives have been characterized on the basis of their elemental analyses, conductance measurements and spectral (IR, 1H-NMR, UV-VIS) studies. - keywords: Bis(indenyl)zirconium(IV) complexes; Schiff base; Conductance; IR; 1H-NMR; UV-VIS
