63700-90-3

Upstream product

• 69877-38-9 5-(4-methoxy-2,3,6-trimethylphenyl)-3-methyl-2(E),4(E)-pentadien-1-al 
• 2124-87-0 trans-4-Diaethylphosphono-4-fluor-3-methyl-crotonsaeure-aethylester 
• 76186-97-5 2,3,6-trimethyl-4-methoxybenzyltriphenyl-phosphonium chloride 
• 69877-73-2 (E,Z,E)-3,7-dimethyl-4-fluoro-8-oxo-2,4,6-octatrienoate 
• 63651-18-3 7-(4-methoxy-2,3,6-trimethylphenyl)-2-fluoro-5-methyl-2(Z),4(E),6(E)-heptatrienoic acid, ethyl ester 
• 63651-19-4 (2Z,4E,6E)-2-Fluoro-7-(4-methoxy-2,3,6-trimethyl-phenyl)-5-methyl-hepta-2,4,6-trienoic acid 
• 62924-31-6 1-(2,5,6-trimethyl-4-methoxyphenyl)-but-1-en-3-one 
• 69877-72-1 (E,Z/E,E)-3,7-dimethyl-4-fluoro-8-oxo-2,4,6-octatrienoate 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 69877-41-4 8-(4-methoxy-2,3,6-trimethylphenyl)-3-fluoro-6-methyl-3(Z),5(E),7(E)-octatrien-2-one 

Relevant academic research and scientific papers

Fluorinated Retinoic Acids and Their Analogues. 2. Synthesis and Biological Activity of Aromatic 4-Fluoro Analogues

Ethyl (E,Z,E,E)-3,7-dimethyl-4-fluoro-9-(4-methoxy-2,3,6-trimethylphenyl)nonatetraenoate (10a) has been found to cause a marked regression of chemically induced skin papillomas in mice.A new synthesis of this compound was achieved by condensation of 4-flu

Fluorinated aromatic polyenes

Compounds represented by the formula STR1 wherein R1, R2 and R3 are lower alkyl, R4 is lower alkoxy, R6 and R8 are methyl or trifluoro methyl, R9 is formyl, hydroxymethyl, alkoxymethyl, alkanoyloxymethyl, carboxyl, alkoxycarbonyl, lower alkenoxycarbonyl, lower alkynoxycarbonyl, carbamoyl, mono(lower alkyl)-carbamoyl, di(lower alkyl)carbamoyl or N-heterocyclylcarbonyl, R5, R7, R10, R11, R12 and R13 are hydrogen or fluorine with the proviso that at least one of R5, R7, R10, R11, R12 or R13 is fluorine or at least one of R6 or R8 is trifluoro methyl, or pharmaceutically acceptable salts thereof useful as antitumor agents are disclosed.