637009-13-3Relevant academic research and scientific papers
Syntheses of showdomycin and its anomer using N-(triisopropylsilyl)pyrrole as a synthetic equivalent for the maleimide C3-anion
Hungerford, Natasha L.,Armitt, David J.,Banwell, Martin G.
, p. 1837 - 1843 (2007/10/03)
Showdomycin (1) and its anomer (2) have been prepared in four steps from readily available trichloroacetimidate 9. The key step involves reaction of the last compound with the title pyrrole 3 so as to form a chromatographically separable mixture of the pyrrole C-glycosides 10 and 11. These pyrroles are desilylated then oxidized to the corresponding maleimides using PCC.
