637027-27-1

Basic information

• Product Name: 1-[4-(4-fluorophenoxy)-3,5-difluorophenyl]sulfonyl-4-boc-piperazine-2-(R)-carboxylic acid
• Synonyms: 1-[4-(4-fluorophenoxy)-3,5-difluorophenyl]sulfonyl-4-boc-piperazine-2-(R)-carboxylic acid
• CAS NO: 637027-27-1
• Molecular Weight: 516.495
• Mol File: 637027-27-1.mol

Chemical Properties

• CAS DataBase Reference: 1-[4-(4-fluorophenoxy)-3,5-difluorophenyl]sulfonyl-4-boc-piperazine-2-(R)-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(4-fluorophenoxy)-3,5-difluorophenyl]sulfonyl-4-boc-piperazine-2-(R)-carboxylic acid(637027-27-1)
• EPA Substance Registry System: 1-[4-(4-fluorophenoxy)-3,5-difluorophenyl]sulfonyl-4-boc-piperazine-2-(R)-carboxylic acid(637027-27-1)

Safety Data

• Hazardous Substances Data: 637027-27-1(Hazardous Substances Data)

Upstream product

• 192330-11-3 (R)-4-(tert-butoxycarbonyl)piperazine-2-carboxylic acid 

Relevant articles and documents

HUMAN ADAM-10 INHIBITORS

The present invention provides compounds useful for inhibiting the ADAM-10 protein, with selectivity versus MMP-1. Such compounds are useful in the in vitro study of the role of ADAM-10 (and its inhibition) in biological processes. The present invention also comprises pharmaceutical compositions comprising one or more ADAM-10 inhibitors according to the invention in combination with a pharmaceutically acceptable carrier. Such compositions are useful for the treatment of cancer, arthritis, and diseases related to angiogenesis. Correspondingly, the invention also comprises methods of treating forms of cancer, arthritis, and diseases related to angiogenesis in which ADAM-10 plays a critical role.