637029-03-9Relevant academic research and scientific papers
Benzodiazepine-based selective inhibitors of mitochondrial F 1F0 ATP hydrolase
Hamann, Lawrence G.,Ding, Charles Z.,Miller, Arthur V.,Madsen, Cort S.,Wang, Paulina,Stein, Philip D.,Pudzianowski, Andrew T.,Green, David W.,Monshizadegan, Hossain,Atwal, Karnail S.
, p. 1031 - 1034 (2004)
A series of benzodiazepine-based inhibitors of mitochondrial F 1F0 ATP hydrolase were prepared and evaluated for their ability to selectively inhibit the enzyme in the forward direction. Compounds from this series showed excellent po
THERAPEUTIC INHIBITORS OF THE REVERSE MODE OF ATP SYNTHASE
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Page/Page column 23, (2018/08/12)
Compounds of the following formula, and pharmaceutically-acceptable salts, solvates, hydrates and prodrugs thereof, formula (A) are useful to preferentially inhibit the ATP-hydrolysing mode of ATP synthase, and are thereby useful for treating various dise
Benzodiazepine inhibitors of mitochondial F1F0 ATP hydrolase and methods of inhibiting F1F0 ATP hydrolase
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Page/Page column 14, (2010/02/05)
Compounds having the formula (I), are useful as inhibitors of mitochondrial F1F0 ATP hydrolase, wherein R1, R5 and R7 are optional substituents, R2, R3 and R4 are hydr
