637031-86-8 Usage
General Description
The chemical (3,3-difluorocyclobutoxy)Methyl)benzene is a compound with the molecular formula C12H12F2O. It is a benzene derivative that contains a (3,3-difluorocyclobutoxy)methyl group attached to the benzene ring. ((3,3-difluorocyclobutoxy)Methyl)benzene is a type of fluorinated benzene and is used in various chemical and pharmaceutical applications. Its structure and properties make it suitable for use as a building block in the synthesis of other organic compounds. The incorporation of fluorine atoms in the cyclobutoxy group can result in changes in the chemical and physical properties of the molecule, making it of interest for research and development in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 637031-86-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,7,0,3 and 1 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 637031-86:
(8*6)+(7*3)+(6*7)+(5*0)+(4*3)+(3*1)+(2*8)+(1*6)=148
148 % 10 = 8
So 637031-86-8 is a valid CAS Registry Number.
637031-86-8Relevant articles and documents
Multigram Synthesis of C 4/C5 3,3-Difluorocyclobutyl-Substituted Building Blocks
Melnykov, Kostiantyn P.,Granat, Dmitriy S.,Volochnyuk, Dmitriy M.,Ryabukhin, Sergey V.,Grygorenko, Oleksandr O.
, p. 4949 - 4957 (2018/12/13)
An approach for the multigram synthesis of 3,3-difluorocyclobutyl-substituted building blocks (including carboxylic acid, amines, alcohols, azide, trifluoroborate ketone) is described. It is shown that, in most cases, ethyl 3,3-difluorocyclobutanecarboxylate is a convenient common synthetic intermediate to obtain the target derivatives. For preparation of 3,3-difluorocyclobutanol or -cyclobutanone, an alternative pathway via reaction of dichloroketene and tert -butyl or benzyl vinyl ether should be applied.
