637038-75-6

Upstream product

• 54435-09-5 2-iodo-4-methoxybenzoic acid 
• 106-95-6 allyl bromide 
• 100-09-4 4-methoxybenzoic acid 

Downstream Products

• 681171-45-9 3-methoxy-6-ethyl-phenethyl alcohol 
• 79928-69-1 2-formyl-5-methoxyallylbenzene 
• 57839-47-1 6-methoxy-1-phenyl-3,4-dihydro-1H-isochromene 
• 1379305-58-4 C₁₁H₁₁ClO₂ 
• 102041-35-0 2-Allyl-4-methoxybenzyl alcohol 

Relevant academic research and scientific papers

Palladium-Catalyzed Alkene Thioacylation: A C?S Bond Activation Approach for Accessing Indanone Derivatives

A palladium-catalyzed intramolecular alkene thioacylation reaction initiated by the activation of thioester C(acyl)?S bonds is reported. This approach successfully suppressed decarbonylation and β-hydrogen elimination with related acyl and alkyl metal thiolate intermediates, providing an efficient and atom-economical method to access indanone scaffolds. Mechanistic studies provide support for C(acyl)?Pd bond insertion of olefins. The synthetic utility of this protocol is demonstrated by the further conversion of the newly formed methylene sulfide substituent. (Figure presented.).

Direct benzylic C-H activation for C-O bond formation by photoredox catalysis

Power of light: 1,4-dicyanonaphthalene (DCN) and light directly activates benzylic C-H bonds for intra- and intermolecular C-O bond formation. Arylalkyls have also been transformed directly into aryl ketones using water as a source of oxygen. EDG=electron-donating group, EWG=electron-withdrawing group. Copyright