63714-95-4Relevant academic research and scientific papers
Hydrogenation of coumarin to octahydrocoumarin over a Ru/C catalyst
Bílková, Dana,Jansa, Petr,Paterová, Iva,?erveny, Libor
, p. 957 - 960 (2015/07/01)
The production of octahydrocoumarin, which can serve as a replacement for toxic coumarin, was investigated using 5% Ru on active carbon (Ru/C) as the catalyst for the hydrogenation of coumarin. The hydrogenation was studied by optimizing the reaction conditions (pressure, solvent and coumarin concentration). The activity and selectivity of the Ru/C catalyst were compared for different solvents. The mechanism of coumarin hydrogenation was deduced. The formation of side products was explained. The optimal hydrogenation reaction conditions were: 130 °C, 10 MPa, 60 wt% coumarin in methanol, and 0.5 wt% (based on coumarin) of Ru/C catalyst. At the complete conversion of coumarin, the selectivity to the desired product was 90%.
Cobalt mediated regioselective ring opening of oxiranes with benzenethiol: A mechanistic study
Iqbal, Javed,Pandey, Anu,Shukla, Alka,Srivastava, Rajiv Ranjan,Tripathi, Sanjay
, p. 6423 - 6432 (2007/10/02)
: Oxiranes are regioselectively cleaved by benzenethiol in presence of cobalt(II) chloride or Co2(CO)8 to the corresponding β-hydroxy sulfides in good yields. A mechanistic study of this reaction reveals that an electron transfer process is involved in these transformations and the reaction is proceeding via the formation of a carbon-cobalt bond.
