6373-69-9

Basic information

• Product Name: 4-Chloro-N-(4-methoxyphenyl)-2-nitroaniline
• Synonyms: 4-Chloro-N-(4-methoxyphenyl)-2-nitroaniline;Amacel Golden Orange 3G;C.I.10350;C.I.Disperse Orange 15;(4-Chloro-2-nitro-phenyl)-(4-methoxy-phenyl)-amine
• CAS NO: 6373-69-9
• Molecular Formula: C₁₃H₁₁ClN₂O₃
• Molecular Weight: 278.69
• Mol File: 6373-69-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 399.9°C at 760 mmHg
• Flash Point: 195.7°C
• Appearance: /
• Density: 1.371g/cm³
• Vapor Pressure: 1.32E-06mmHg at 25°C
• Refractive Index: 1.645
• CAS DataBase Reference: 4-Chloro-N-(4-methoxyphenyl)-2-nitroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-N-(4-methoxyphenyl)-2-nitroaniline(6373-69-9)
• EPA Substance Registry System: 4-Chloro-N-(4-methoxyphenyl)-2-nitroaniline(6373-69-9)

Safety Data

• Hazardous Substances Data: 6373-69-9(Hazardous Substances Data)

Usage

Preparation

2,5-Dichloronitrobenzene and p-anisidine?condensation

Properties and Applications

Bright yellow orange. Insoluble in water, but soluble in ethanol is yellow, the strong sulfuric acid in the dye solution colorless, diluted unchanged. Standard Ironing Fastness Light Fastness Persperation Fastness Washing Fastness Fading Stain Fading Stain Fading Stain AATCC 7 4 4 3 3

Standard

Ironing Fastness

Fading

Stain

InChI:InChI=1/C13H11ClN2O3/c1-19-11-5-3-10(4-6-11)15-12-7-2-9(14)8-13(12)16(17)18/h2-8,15H,1H3

Upstream product

• 104-94-9 4-methoxy-aniline 
• 89-61-2 2,5-dichloronitrobenzene 
• 1448355-81-4 potassium 2-nitro-4-chlorobenzoate 

Downstream Products

• 1750-94-3 4-Chloro-N₁-(4-methoxyphenyl)benzene-1,2-diamine 
• 18450-08-3 2-Chlor-8-methoxy-phenazin 

Relevant articles and documents

Decarboxylative ipso Amination of Activated Benzoic Acids

In the presence of a bimetallic Pd/Cu system with 1,10-phenanthroline as the ligand and either air or N-methylmorpholine N-oxide as the oxidant, electron-deficient benzoic acids undergo oxidative decarboxylative coupling with unprotected amines. This operationally simple aniline synthesis is widely applicable with respect to the amine and gives good yields, even on multigram scale. The orthogonality of this reaction to other Pd-catalyzed cross-couplings allows the concise synthesis of multisubstituted arenes by sequential C?C, C?Cl, and C?N functionalizations. Mechanistic investigations suggest the intermediacy of a hypervalent Pd species.

RECEPTOR FUNCTION REGULATING AGENT

The present invention relates to a GPR40 receptor function regulator comprising a fused imidazole compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof or a prodrug thereof. The GPR40 receptor funct