6373-69-9

Usage

Uses

Used in Dye Industry:
4-Chloro-N-(4-methoxyphenyl)-2-nitroaniline is used as a dye in the textile industry for its bright yellow-orange color. Its solubility in ethanol makes it suitable for dyeing fabrics, and its colorfastness properties ensure that the color remains stable under various conditions.
Used in Textile Industry:
4-Chloro-N-(4-methoxyphenyl)-2-nitroaniline is used as a colorant in the textile industry to impart a bright yellow-orange hue to fabrics. Its properties, such as ironing fastness, light fastness, perspiration fastness, and washing fastness, make it a reliable choice for long-lasting color in textiles.
The AATCC (American Association of Textile Chemists and Colorists) test results indicate the colorfastness ratings for 4-Chloro-N-(4-methoxyphenyl)-2-nitroaniline in various conditions:
Ironing Fastness: 7
Light Fastness: 4
Perspiration Fastness: 4
Washing Fastness: 3
These ratings demonstrate the compound's performance in maintaining color under different conditions, making it a valuable dye for the textile industry.

Preparation

2,5-Dichloronitrobenzene and p-anisidine?condensation

Standard

Ironing Fastness

Fading

Stain

InChI:InChI=1/C13H11ClN2O3/c1-19-11-5-3-10(4-6-11)15-12-7-2-9(14)8-13(12)16(17)18/h2-8,15H,1H3

Upstream product

• 104-94-9 4-methoxy-aniline 
• 89-61-2 2,5-dichloronitrobenzene 
• 1448355-81-4 potassium 2-nitro-4-chlorobenzoate 

Downstream Products

• 1750-94-3 4-Chloro-N₁-(4-methoxyphenyl)benzene-1,2-diamine 
• 18450-08-3 2-Chlor-8-methoxy-phenazin 

Relevant academic research and scientific papers

Decarboxylative ipso Amination of Activated Benzoic Acids

In the presence of a bimetallic Pd/Cu system with 1,10-phenanthroline as the ligand and either air or N-methylmorpholine N-oxide as the oxidant, electron-deficient benzoic acids undergo oxidative decarboxylative coupling with unprotected amines. This operationally simple aniline synthesis is widely applicable with respect to the amine and gives good yields, even on multigram scale. The orthogonality of this reaction to other Pd-catalyzed cross-couplings allows the concise synthesis of multisubstituted arenes by sequential C?C, C?Cl, and C?N functionalizations. Mechanistic investigations suggest the intermediacy of a hypervalent Pd species.

Synthesis and biological evaluation of novel pyrazole carboxamide with diarylamine-modi?ed scaffold as potent antifungal agents

Twenty-seven novel pyrazole carboxamides with diarylamine-modi?ed scaffold were designed, synthesized and characterized in detail via 1H NMR, 13C NMR, IR and ESI-HRMS. Preliminary bioassays showed that some of the target compounds exhibited good antifungal activity against Rhizoctonia solani, Rhizoctonia cerealis and Sclerotinia sclerotiorum. Among them, compound 9c-7 exhibited the highest antifungal activities against R. solani, R. cerealis and S. sclerotiorum in vitro with IC50 values of 0.013, 1.608 and 1.874?μg/mL, respectively. Notably, compound 9c-7 still presented the highest fungicidal activities against R. solani in vivo with an IC50 value of 22.21?μg/mL. Molecular docking simulation results reveal that compound 9c-7 binds well to the hydrophobic pockets of the receptor protein succinate dehydrogenase. This study suggests that compound 9c-7 could act as a potential fungicide to be used for further optimization.

RECEPTOR FUNCTION REGULATING AGENT

The present invention relates to a GPR40 receptor function regulator comprising a fused imidazole compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof or a prodrug thereof. The GPR40 receptor funct