637338-78-4 Usage
Uses
Used in Chemical Research:
3-chloro-1H-pyrazolo[3,4-d]pyrimidin-4-amine is used as a research compound for the exploration of its chemical properties and potential applications in various fields. Its unique structure, which includes a pyrazole ring, a pyrimidine ring, an amine group, and a chlorine atom, makes it an interesting candidate for study in the development of new chemical processes or materials.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 3-chloro-1H-pyrazolo[3,4-d]pyrimidin-4-amine is used as a starting material or intermediate in the synthesis of potential drug candidates. Its chemical structure may be further modified to create new compounds with therapeutic properties, making it a valuable component in the development of novel medications.
Used in Material Science:
3-chloro-1H-pyrazolo[3,4-d]pyrimidin-4-amine may also be utilized in material science applications, where its unique structure could contribute to the development of new materials with specific properties. Researchers may explore its potential use in the creation of advanced materials for various industries, such as electronics, energy, or aerospace.
Check Digit Verification of cas no
The CAS Registry Mumber 637338-78-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,7,3,3 and 8 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 637338-78:
(8*6)+(7*3)+(6*7)+(5*3)+(4*3)+(3*8)+(2*7)+(1*8)=184
184 % 10 = 4
So 637338-78-4 is a valid CAS Registry Number.
637338-78-4Relevant academic research and scientific papers
A conformational mimetic approach for the synthesis of carbocyclic nucleosides as anti-HCV leads
Kasula, Mohan,Balaraju, Tuniki,Toyama, Massaki,Thiyagarajan, Anandarajan,Bal, Chandralata,Baba, Masanori,Sharon, Ashoke
supporting information, p. 1673 - 1680 (2013/10/21)
Computer-aided approaches coupled with medicinal chemistry were used to explore novel carbocyclic nucleosides as potential anti-hepatitisC virus (HCV) agents. Conformational analyses were carried out on 6-amino-1H-pyrazolo[3,4-d]pyrimidine (6-APP)-based carbocyclic nucleoside analogues, which were considered as nucleoside mimetics to act as HCV RNA-dependent RNA polymerase (RdRp) inhibitors. Structural insight gained from the modeling studies revealed the molecular basis behind these nucleoside mimetics. The rationally chosen 6-APP analogues were prepared and evaluated for anti-HCV activity. RdRp SiteMap analysis revealed the presence of a hydrophobic cavity near C7 of the nucleosides; introduction of bulkier substituents at this position enhanced their activity. Herein we report the identification of an iodinated compound with an EC50 value of 6.6μM as a preliminary anti-HCV lead.
Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis
-
, (2008/06/13)
Oligonucleotide probes/conjugates are provided along with method for their use in assays to monitor amplification wherein the signal produced does not rely on 5′ nuclease digestion.
