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637338-78-4

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637338-78-4 Usage

General Description

3-chloro-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a chemical compound that belongs to the class of organic compounds known as pyrazolopyrimidines. Its molecular formula is C6H5ClN6, and it possesses a molar mass of 200.59 g/mol. The chemical's IUPAC name is 3-chloro-1H-pyrazolo[3,4-d]pyrimidin-4-amine, indicating its structure includes a pyrazole ring, a pyrimidine ring, an amine group, and a chlorine atom. While it's used in chemical research, its specific applications, potential reactivity, and health and safety information may vary and typically require further study or specific context.

Check Digit Verification of cas no

The CAS Registry Mumber 637338-78-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,7,3,3 and 8 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 637338-78:
(8*6)+(7*3)+(6*7)+(5*3)+(4*3)+(3*8)+(2*7)+(1*8)=184
184 % 10 = 4
So 637338-78-4 is a valid CAS Registry Number.

637338-78-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-chloro-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine

1.2 Other means of identification

Product number -
Other names 3-chloro-1H-Pyrazolo[3,4-d]pyrimidin-4-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:637338-78-4 SDS

637338-78-4Relevant articles and documents

A conformational mimetic approach for the synthesis of carbocyclic nucleosides as anti-HCV leads

Kasula, Mohan,Balaraju, Tuniki,Toyama, Massaki,Thiyagarajan, Anandarajan,Bal, Chandralata,Baba, Masanori,Sharon, Ashoke

supporting information, p. 1673 - 1680 (2013/10/21)

Computer-aided approaches coupled with medicinal chemistry were used to explore novel carbocyclic nucleosides as potential anti-hepatitisC virus (HCV) agents. Conformational analyses were carried out on 6-amino-1H-pyrazolo[3,4-d]pyrimidine (6-APP)-based carbocyclic nucleoside analogues, which were considered as nucleoside mimetics to act as HCV RNA-dependent RNA polymerase (RdRp) inhibitors. Structural insight gained from the modeling studies revealed the molecular basis behind these nucleoside mimetics. The rationally chosen 6-APP analogues were prepared and evaluated for anti-HCV activity. RdRp SiteMap analysis revealed the presence of a hydrophobic cavity near C7 of the nucleosides; introduction of bulkier substituents at this position enhanced their activity. Herein we report the identification of an iodinated compound with an EC50 value of 6.6μM as a preliminary anti-HCV lead.

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