637352-84-2 Usage
Description
2-Chloro-6-[4-(trifluoromethyl)phenyl]pyrazine, a pyrazine derivative with the molecular formula C10H5ClF3N3, features a chlorine atom at position 2 and a trifluoromethylphenyl group at position 6. This chemical compound is known for its unique molecular structure and properties, which make it a promising candidate in various fields such as pharmaceuticals, agrochemicals, and materials science. It serves as an intermediate in the synthesis of organic compounds and as a building block for developing new drugs and materials. Due to its potential applications and reactivity, it is crucial to handle this compound with care and adhere to safety protocols in laboratory settings.
Uses
Used in Pharmaceutical Industry:
2-Chloro-6-[4-(trifluoromethyl)phenyl]pyrazine is used as an intermediate in the synthesis of various organic compounds for pharmaceutical applications. Its unique molecular structure contributes to the development of new drugs with potential therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Chloro-6-[4-(trifluoromethyl)phenyl]pyrazine is utilized as a building block for the creation of new agrochemicals, potentially enhancing crop protection and yield.
Used in Materials Science:
2-Chloro-6-[4-(trifluoromethyl)phenyl]pyrazine is employed in materials science for the development of novel materials with specific properties, such as improved stability or reactivity, due to its distinctive molecular structure.
Check Digit Verification of cas no
The CAS Registry Mumber 637352-84-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,7,3,5 and 2 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 637352-84:
(8*6)+(7*3)+(6*7)+(5*3)+(4*5)+(3*2)+(2*8)+(1*4)=172
172 % 10 = 2
So 637352-84-2 is a valid CAS Registry Number.
637352-84-2Relevant articles and documents
Palladium-catalyzed cross-coupling of aroyl chlorides with aryl stannanes in the presence of triethylsilane: Efficient access to aromatic ketones
Higashi, Shoko,Uno, Sota,Ohsuga, Yui,Noumi, Maiko,Saito, Ryota
supporting information, (2020/10/12)
Herein, we report the development of a palladium-catalyzed cross-coupling reaction that focuses on the preparation of aromatic ketones. Aroyl chlorides react quickly at 120 °C with aryl stannanes in the presence of Pd(PPh3)4 and Et3SiH to efficiently give the corresponding ketones without the formation of significant decarbonylated byproducts. In other words, the decarbonylative side reaction is practically suppressed by simply adding Et3SiH to the reaction mixture, which reduces the amount of biaryl impurities in the products.
BENZOAZEPIN-OXY-ACETIC ACID DERIVATIVES AS PPAR-DELTA AGONISTS USED FOR THE INCREASE OF HDL-C, LOWER LDL-C AND LOWER CHOLESTEROL
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Page/Page column 82, (2008/06/13)
The invention is directed to compounds of Formula (I) useful as PPAR agonists. Pharmaceutical compositions and methods of treating one or more conditions including, but not limited to, diabetes, nephropathy, neuropathy, retinopathy, polycystic ovary syndr
