637362-71-1

Basic information

• Product Name: C₂₉H₃₄N₂O₅
• Synonyms: C₂₉H₃₄N₂O₅
• CAS NO: 637362-71-1
• Molecular Weight: 490.599
• Mol File: 637362-71-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₂₉H₃₄N₂O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₉H₃₄N₂O₅(637362-71-1)
• EPA Substance Registry System: C₂₉H₃₄N₂O₅(637362-71-1)

Safety Data

• Hazardous Substances Data: 637362-71-1(Hazardous Substances Data)

Upstream product

• 288399-19-9 4-(chloromethyl)-2-methylquinoline 
• 611227-65-7 (R)-ethyl 2-(tert-butoxycarbonyl)-2-(4-hydroxyphenyl)pent-4-enoate 
• 637752-12-6 C₂₄H₂₆N₂O₃ 
• 24424-99-5 di-tert-butyl dicarbonate 

Relevant articles and documents

Development and large-scale preparation of an oral TACE inhibitor

An efficient, expedient synthesis of BMS-561392, 1, which enabled rapid delivery of drug substance for clinical development is described. The key features of the synthesis include an efficient synthesis of a phenolic α,α-disubstituted amino ester via carbon alkylation without protection of the phenol, an effective enzymatic resolution of this racemic amino ester, and a process for the preparation of a hydroxamic acid drug substance with undetectable levels of hydroxylamine.

DPC 333 formulation having unique biopharmaceutical characteristics

Oral dosage forms of the crystalline, free base of ([1-(R)]-3-amino-N-hydroxy-alpha-(2-methylpropyl)-3-[4-[(2-methyl-4-quinolinyl)methoxy]phenyl]-2-oxo-1-pyrrolidineacetamide, referred to herein as DPC 333, having unique biopharmaceutical characteristics