637363-42-9Relevant articles and documents
Synthesis and biological evaluation of substrate-based inhibitors of 6-phosphogluconate dehydrogenase as potential drugs against African trypanosomiasis
Dardonville, Christophe,Rinaldi, Eliana,Hanau, Stefania,Barrett, Michael P.,Brun, Reto,Gilbert, Ian H.
, p. 3205 - 3214 (2007/10/03)
The synthesis and biological evaluation of three series of 6-phosphogluconate (6PG) analogues is described. (2R)-2-Methyl-4,5-dideoxy, (2R)-2-methyl-4-deoxy and 2,4-dideoxy analogues of 6PG were tested as inhibitors of 6-phosphogluconate dehydrogenase (6P