637363-46-3

Upstream product

• 637363-45-2 (S)-4-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3-hydroxy-butyric acid benzyl ester 
• 637363-43-0 (4R)-4-benzyl-3-[4-((4S)-2,2-dimethyl-1,3-dioxolan-4-yl)-3-(3S)-hydroxybutanoyl]-1,3-oxazolan-2-one 
• 637363-44-1 (S)-4-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3-hydroxy-butyric acid 

Downstream Products

• 637363-48-5 (3S,5S)-6-(Bis-benzyloxy-phosphoryloxy)-3,5-dihydroxy-hexanoic acid benzyl ester 

Relevant academic research and scientific papers

Synthesis and biological evaluation of substrate-based inhibitors of 6-phosphogluconate dehydrogenase as potential drugs against African trypanosomiasis

The synthesis and biological evaluation of three series of 6-phosphogluconate (6PG) analogues is described. (2R)-2-Methyl-4,5-dideoxy, (2R)-2-methyl-4-deoxy and 2,4-dideoxy analogues of 6PG were tested as inhibitors of 6-phosphogluconate dehydrogenase (6P