63744-29-6 Usage
Uses
Used in Pharmaceutical Industry:
5-Bromo-[1,2,4]triazolo[4,3-a]pyrazine is used as a key intermediate for the production of pharmaceutical drugs. Its unique structure and properties make it valuable in the synthesis of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 5-Bromo-[1,2,4]triazolo[4,3-a]pyrazine is utilized as an intermediate in the development of agrochemicals. Its reactivity and structural features contribute to the creation of new compounds with potential applications in agriculture, such as pesticides and herbicides.
Used in Material Science:
5-Bromo-[1,2,4]triazolo[4,3-a]pyrazine is employed in the development of new materials and chemical processes. Its unique properties allow for the creation of innovative materials with specific characteristics, such as improved stability or reactivity.
Used in Chemical Research:
As a highly reactive compound, 5-Bromo-[1,2,4]triazolo[4,3-a]pyrazine is used in chemical research to explore new reactions and mechanisms. Its potential applications in various chemical processes make it a valuable tool for advancing the field of organic chemistry.
Due to the potential health and environmental risks associated with 5-Bromo-[1,2,4]triazolo[4,3-a]pyrazine, it is crucial to follow proper handling and disposal procedures when working with 5-BroMo-[1,2,4]triazolo[4,3-a]pyrazine.
Check Digit Verification of cas no
The CAS Registry Mumber 63744-29-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,7,4 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 63744-29:
(7*6)+(6*3)+(5*7)+(4*4)+(3*4)+(2*2)+(1*9)=136
136 % 10 = 6
So 63744-29-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H3BrN4/c6-4-1-7-2-5-9-8-3-10(4)5/h1-3H
63744-29-6Relevant academic research and scientific papers
tele-Substitution Reactions in the Synthesis of a Promising Class of 1,2,4-Triazolo[4,3- a]pyrazine-Based Antimalarials
Korsik, Marat,Tse, Edwin G.,Smith, David G.,Lewis, William,Rutledge, Peter J.,Todd, Matthew H.
, p. 13438 - 13452 (2020/12/15)
We have discovered and studied a tele-substitution reaction in a biologically important heterocyclic ring system. Conditions that favor the tele-substitution pathway were identified: the use of increased equivalents of the nucleophile or decreased equivalents of base or the use of softer nucleophiles, less polar solvents, and larger halogens on the electrophile. Using results from X-ray crystallographic and isotope labeling experiments, a mechanism for this unusual transformation is proposed. We focused on this triazolopyrazine as it is the core structure of the in vivo active antiplasmodium compounds of Series 4 of the Open Source Malaria consortium.
