6375-02-6

Basic information

• Product Name: 5-Amino-2-ethoxy-benzenesulfonic acid
• Synonyms: 5-AMINO-2-ETHOXY-BENZENESULFONIC ACID;P-PHENETIDINE-3-SULFONIC ACID;6-Ethoxymetanilic acid
• CAS NO: 6375-02-6
• Molecular Formula: C₈H₁₁NO₄S
• Molecular Weight: 217.24
• EINECS: 228-929-9
• Mol File: 6375-02-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 596.3°C at 760 mmHg
• Flash Point: 314.4°C
• Appearance: /
• Density: 1.401 g/cm³
• Vapor Pressure: 3.48E-14mmHg at 25°C
• Refractive Index: 1.637
• CAS DataBase Reference: 5-Amino-2-ethoxy-benzenesulfonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Amino-2-ethoxy-benzenesulfonic acid(6375-02-6)
• EPA Substance Registry System: 5-Amino-2-ethoxy-benzenesulfonic acid(6375-02-6)

Safety Data

• Hazardous Substances Data: 6375-02-6(Hazardous Substances Data)

Usage

General Description

5-Amino-2-ethoxy-benzenesulfonic acid, also known as AEBSF, is a chemical compound commonly used as a serine protease inhibitor. It is often employed in research and laboratory settings to prevent the degradation of proteins by serine proteases. AEBSF works by irreversibly inhibiting the enzymatic activity of serine proteases, and it is particularly effective against a wide range of proteases, making it a versatile and valuable tool in biochemical and biomedical research. Additionally, it is known for its stability and solubility in water, making it easy to handle and use in various experimental procedures. Overall, 5-Amino-2-ethoxy-benzenesulfonic acid is a crucial and widely-used chemical in protease inhibition and protein research.

InChI:InChI=1/C19H17ClN2O3S/c1-12-9-15(5-6-16(12)20)25-8-7-24-14-4-2-3-13(10-14)11-17-18(23)22-19(21)26-17/h2-6,9-11H,7-8H2,1H3,(H2,21,22,23)/b17-11-

Upstream product

• 7664-93-9 sulfuric acid 
• 156-43-4 4-Ethoxyaniline 
• 62-44-2 4-ethoxyacetanilide 

Relevant articles and documents

Amino disazo dyestuffs containing a fluoropyrimidinyl or a fluorotriazinyl reactive group

Dyestuffs of the formula STR1 wherein X=--CH=CH2, --CH2 --CH2 OSO3 H, --CH=CHCl or --CH2 --CH2 Cl and Y=a fiber-reactive fluoropyrimidinyl or fluorotriazine radical and wherein u and v=H or SO3 H, where u~v. Such dyestuffs suitable for dyeing and printing diverse substrates, particularly cotton, to give products a high degree of dyestuff fixation.

Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member

A reactive dye of the formula STR1 in which: F is a radical selected from the group consisting of metal-free or metal-containing monoazo or disazo dyes containing at least one --SO3 H group, anthraquinone dyes, sulfophthalocyanine dyes, formazan dyes, phenazine dyes, oxazine dyes and nitroaryl dyes, R is hydrogen, C1 -C4 alkyl which is unsubstituted or substituted with --COOH or --SO3 H, cyanoethyl, or hydroxyethyl, X is fluorine, chlorine, bromine, --SO3 H, phenylsulfonyl or C1 -C4 -alkylsulfonyl, p is 1 or 2 and A is a radical of the formula STR2 in which: Y is chlorine, bromine, fluorine, --OH, --OSO3 H, --O-acyl, --CN, --COOH, --COO--C1 -C4 -alkyl, --CONH2 or --SO2 --Z, the group designated "alk" is a straight or branched polymethylene radical having 2 to 6 carbon atoms, V is STR3 hydrogen or C1 -C4 -alkyl which is unsubstituted or substituted by C1 -C2 -alkoxy, carboxyl, sulfo, halogen or hydroxy, Z is β-halogenoethyl, vinyl or β-acetoxyethyl, or A is a radical of the formulae STR4 in all of which R' is C1-6 -alkyl or hydrogen, Z is as defined above, o is 0 to 6, and m is 2 to 6.

SYNTHESIS AND PROPERTIES OF SULFATE SALTS OF PARA-SUBSTITUTED AROMATIC AMINES

-