63754-98-3

Usage

General Description

6-Chloro-3-Methylbenzo[d]thiazol-2(3H)-one is a chemical compound with the molecular formula C9H6ClNOS. It is a thiazolone derivative with a chloro substitution at the 6 position and a methyl group at the 3 position. 6-Chloro-3-Methylbenzo[d]thiazol-2(3H)-one has potential applications in the field of medicinal chemistry, particularly in the development of pharmaceuticals. It may exhibit biological activity and could be used as a building block for the synthesis of other compounds with therapeutic properties. Additionally, it may have other industrial uses such as in the production of dyes, pigments, and agricultural chemicals. Further research and testing are necessary to fully understand the properties and potential applications of 6-Chloro-3-Methylbenzo[d]thiazol-2(3H)-one.

Upstream product

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Relevant academic research and scientific papers

A preparation N-methyl thiazoline-2-ketone compound by the method

The invention discloses a method for preparing an N-Methylthiazoline-2-ketone compound. In an inert atmosphere, an organic solvent is taken as a reaction medium, copper salt and an antioxidant are taken as a catalytic system, and a thiazole compound is oxidized into the N-Methylthiazoline-2-ketone compound through an oxidative methylation reaction. The preparation method disclosed by the invention is higher in reactivity, mild in reaction conditions, short in reaction time and high in yield; used catalysts are low in price and toxicity, and less in use amount, a multi-step reaction is shortened to a one-step reaction, and the treatment is simple, thereby being beneficial to purifying products; most importantly, the use of a toxic and volatile methylation reagent is avoided. The catalyst system disclosed by the invention has universality for a variety of reactants. Raw materials of the invention are readily available, and the reaction process is simple and controllable, so that the method is suitable for the industrialized production.

Copper catalyzed three-component synthesis of benzothiazolones from o-iodoanilines, DMF, and potassium sulfide

A copper catalyzed three-component reaction was developed for the synthesis of benzothiazolones. In the presence of CuBr2, the reaction of o-iodoanilines and K2S with DMF proceeded smoothly and generated the corresponding benzothiazolones with good isolated yields. DMF functioned both as the carbon monoxide source and as the reaction medium in this reaction.